Evidence map›Paper›PMID 41131419›Full record

ReviewMikrochimica acta2025

Biomedical applications of extracellular vesicles (EVs): even better with cryogels.

Almaysh Haidar Rizqullah, Yeşeren Saylan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Almaysh Haidar RizqullahDepartment of Chemistry, Hacettepe University, 06800, Ankara, Turkey.
Yeşeren SaylanDepartment of Chemistry, Hacettepe University, 06800, Ankara, Turkey. yeseren@hacettepe.edu.tr.

Funding

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu 121C226
6 · The paper itself

Abstract

Apoptotic bodies, exosomes, and microvesicles are the three categories into which extracellular vesicles (EVs) can be divided according to their size and biogenesis. Different cell types release exosomes, which are crucial for preserving effective intercellular communication. The macromolecules of exosome membranes, including surface antigens and proteins, hold promising potential as biomarkers due to their ability to provide valuable information about their source. Moreover, the therapeutic potential of exosomes remains a notable research topic, with one aspect being the search for suitable materials for effective delivery. One candidate for such material is cryogels, which are biomaterials prepared below the solvent's freezing point via cross-linking polymer reactions or addition polymerization from monomers, resulting in an elastic, spongy, loose, and porous structure. Cryogels may provide a new avenue for more efficient use of EVs in biomedical fields. This review provides a detailed explanation of the fundamentals of EVs, exosomes, and cryogels. The latest cryogel-based applications of exosomes, the most common among EVs, are discussed after a separate review of each of the current biomedical applications involving the usage of exosomes and cryogels.

Indexed as

CryogelsExtracellular VesiclesAnimalsBiomedical ResearchBiomimetic MaterialsHumansMolecular ImprintingNeoplasmsCryogelsBiomaterialBiomedical applicationsCryogelExosomeExtracellular vesicles

Identifiers

PMID41131419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.