Evidence map›Paper›PMID 41131380›Full record

ArticleSurgical endoscopy2026

Minimally invasive radical surgery for gallbladder cancer: a single-unit experience of over 200 patients.

Anil K Agarwal, B G Vageesh, Amit Javed, Raja Kalayarasan, Vidya S Bhatt, M N Saravanan, Puja Sakhuja

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Anil K AgarwalDepartment of GI Surgery& Pathology, GB Pant Institute of Postgraduate Medical Education & Research and Maulana Azad Medical College, Delhi University, JLN Marg, New Delhi, 110002, India. aka.hpb@gmail.com.
B G VageeshDepartment of GI Surgery& Pathology, GB Pant Institute of Postgraduate Medical Education & Research and Maulana Azad Medical College, Delhi University, JLN Marg, New Delhi, 110002, India.
Amit JavedDepartment of GI Surgery& Pathology, GB Pant Institute of Postgraduate Medical Education & Research and Maulana Azad Medical College, Delhi University, JLN Marg, New Delhi, 110002, India.
Raja KalayarasanDepartment of GI Surgery& Pathology, GB Pant Institute of Postgraduate Medical Education & Research and Maulana Azad Medical College, Delhi University, JLN Marg, New Delhi, 110002, India.
Vidya S BhattDepartment of GI Surgery& Pathology, GB Pant Institute of Postgraduate Medical Education & Research and Maulana Azad Medical College, Delhi University, JLN Marg, New Delhi, 110002, India.
M N SaravananDepartment of GI Surgery& Pathology, GB Pant Institute of Postgraduate Medical Education & Research and Maulana Azad Medical College, Delhi University, JLN Marg, New Delhi, 110002, India.
Puja SakhujaDepartment of GI Surgery& Pathology, GB Pant Institute of Postgraduate Medical Education & Research and Maulana Azad Medical College, Delhi University, JLN Marg, New Delhi, 110002, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost published studies on minimally invasive radical cholecystectomy (MIRC) for gallbladder cancer (GBC) are limited by a small sample size, disproportionately high incidental GBC patients, and a lack of long-term outcomes. The present study aims to report the long-term oncological outcomes of MIRC in a large series of primary and locally advanced GBC patients.

methodsA retrospective analysis was conducted using prospectively collected data from primary and incidental GBC patients who underwent MIRC between March 2011 and June 2023. Patients who underwent MIRC and had benign pathology on final histopathological examination were excluded from the analysis. Perioperative short- and long-term oncological outcomes were analyzed.

resultsDuring the study period, 222 patients with suspected GBC underwent MIRC. The mean age was 49.5 ± 12.5 years with a female-to-male ratio of 4.2:1. The mean operative time and blood loss were 232 ± 55.3 min and 153.8 ± 68.4 mL, respectively. 205 patients with malignancy on final histopathology were included in the analysis of oncological outcomes. The overall median (95% CI) survival, 3-year and 5-year survival rates were 60 (41-62) months, 62.3% and 42.9%, respectively. The median survival was significantly higher in early-stage (T1/T2) GBC compared to locally advanced (T3/T4) tumors (66 vs. 36 months, P < 0.0001). Also, node-negative GBC patients had better overall survival than node-positive tumors (68 vs. 34 months, P < 0.0001). None of the patients had port-site recurrence.

conclusionThe largest single-unit series published to date documents the oncological efficacy of MIRC for GBC.

Indexed as

CholecystectomyCholecystectomy, LaparoscopicGallbladder NeoplasmsAdultAgedFemaleHumansMaleMiddle AgedMinimally Invasive Surgical ProceduresOperative TimeRetrospective StudiesSurvival RateTreatment OutcomeGallbladder cancerLaparoscopic radical cholecystectomyRadical cholecystectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.