Evidence map›Paper›PMID 41131363›Full record

ArticleArchives of gynecology and obstetrics2025

Echocardiographic characteristics of 14 cases with uncommon manifestation of Ebstein anomaly in the fetus: a case series report.

Beilei Huang, Chen Zhou, Haiyan Kuang, Meixiang Zhang, Xiaoliang Huang, Danping Ouyang, Zhirong Wang, Yifan Kong, Yingchun Luo

Abstract read
In one paragraph

Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prenatal sonographic spectrum and first-trimester diagnostic features of Ebstein anomaly: A descriptive case series.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Beilei HuangDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China.
Chen ZhouDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China.
Haiyan KuangDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China.
Meixiang ZhangDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China.
Xiaoliang HuangDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China.
Danping OuyangDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China.
Zhirong WangDepartment of Cardiovascular Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yifan KongDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China.
Yingchun LuoDepartment of Ultrasound, The Maternal and Child Health Care Hospital of Hunan Province, Kaifu District, 53 Xiangchun Road, Changsha, 410008, Hunan, China. 807859088@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was conducted to investigate the diagnostic characteristics of uncommon manifestation of Ebstein Anomaly (EA) during the fetal period, to improve the accuracy of prenatal diagnosis.

methodsThis retrospective analysis was conducted with data from fetuses diagnosed with an uncommon manifestation of EA between January 2020 and October 2024. Maternal and fetal information, prenatal ultrasound data, and information on pregnancy termination/delivery and postnatal surgical treatment were collected.

resultsThe sample comprised 13 with isolated posterior leaflet displacement and 1 with all tricuspid valve leaflets displaced. Four children (two with additional displacement of the septal leaflet detected by postnatal ultrasound) survived. The ultrasound features of isolated posterior leaflet displacement were: (1) normal positioning of the septal and anterior leaflets and significant tricuspid regurgitation with a low starting point of the regurgitant jet on four-chamber view, (2) non-parallel orientation of the line connecting the posterior and anterior leaflet attachment points to that connecting the superior and inferior vena cava on bicaval view, and (3) common association with pulmonary artery stenosis or atresia. Characteristics of the displacement of all leaflets were: (1) downward displacement of all valve leaflets with disruption of the continuity between the septal leaflet and coronary sinus wall, and (2) location of the displaced tricuspid valve orifice at or below the mid-left ventricular level, preventing visualization of the mitral valve, on low short-axis view.

conclusionThe ultrasonic characteristics summarized here enable the accurate prenatal diagnosis of uncommon manifestation of EA. Isolated posterior leaflet displacement may evolve with other morphological anomalies, necessitating regular monitoring.

Indexed as

Ebstein AnomalyEchocardiographyUltrasonography, PrenatalAdultFemaleHumansPregnancyRetrospective StudiesTricuspid ValveTricuspid Valve InsufficiencyAnterior leafletDisplacementEbstein’s anomalyPrenatal diagnosisRare variantTricuspid valve

Identifiers

PMID41131363
PMCPMC12705716

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