Evidence map›Paper›PMID 41131346›Full record

ArticleCommunications biology2025

Comparative venomics suggests an evolutionary adaption of spider venom from predation to defense.

Tim Lüddecke, Sabine Hurka, Josephine Dresler, Thomas Lübcke, Volker von Wirth, Günter Lochnit, Thomas Timm, Volker Herzig, Andreas Vilcinskas

Abstract readComparative Study
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tim LüddeckeBranch for Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Gießen, Germany. tim.lueddecke@ime.fraunhofer.de.ORCID http://orcid.org/0000-0002-7234-8685
Sabine HurkaBranch for Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Gießen, Germany.ORCID http://orcid.org/0000-0003-2083-5198
Josephine DreslerBranch for Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Gießen, Germany.
Thomas LübckeSenckenberg Museum für Naturkunde, Görlitz, Germany.
Volker von WirthTheraphosid Research Team, Eitting, Germany.
Günter LochnitInstitute for Biochemistry, Justus Liebig University of Gießen, Gießen, Germany.ORCID http://orcid.org/0000-0003-0377-395X
Thomas TimmInstitute for Biochemistry, Justus Liebig University of Gießen, Gießen, Germany.
Volker HerzigCentre for Bioinnovation, University of the Sunshine Coast, Sippy Downs, QLD, Australia.ORCID http://orcid.org/0000-0003-2514-3983
Andreas VilcinskasBranch for Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Gießen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most spiders deploy paralytic venom for prey capture, but adults of the Nurse´s thorn finger (Cheiracanthium punctorium) instead produce a predominantly defensive venom to safeguard their offspring. Here, we characterize the molecular repertoire of C. punctorium venom to shed light on its evolutionary history. Unlike venom in other spiders, C. punctorium venom mostly comprises neurotoxic double-domain neurotoxin 19 family (CSTX) peptides and enzymes, such as phospholipase A

Indexed as

Biological EvolutionEvolution, MolecularPredatory BehaviorSpidersSpider VenomsAnimalsNeurotoxinsPhospholipases A2PhylogenyNeurotoxinsPhospholipases A2Spider Venoms

Identifiers

PMID41131346
PMCPMC12550024

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.