Evidence map›Paper›PMID 41131162›Full record

ReviewGenes and immunity2025

Taxonomic variation in immune response strategies among primates.

Sophie K Joseph, Jordan M Lucore, John Lindo, Elizabeth V Lonsdorf, Marcela E Benítez

Abstract readReview
In one paragraph

Review in Genes and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sophie K JosephDepartment of Anthropology, Emory University, Atlanta, GA, USA. skjoseph@berkeley.edu.ORCID 0000-0002-4660-6513
Jordan M LucoreDepartment of Anthropology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-2759-7412
John LindoDepartment of Anthropology, Emory University, Atlanta, GA, USA.ORCID 0000-0002-2533-8505
Elizabeth V LonsdorfDepartment of Anthropology, Emory University, Atlanta, GA, USA.ORCID 0000-0001-8057-401X
Marcela E BenítezDepartment of Anthropology, Emory University, Atlanta, GA, USA. marcela.benitez@emory.edu.ORCID 0000-0001-7425-9507

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In primates, mechanisms of both innate and adaptive immunity are well-studied in just a few species out of this very diverse taxonomic order, especially in relation to specific pathogens like SIV. Recent research has indicated there may be taxon-specific differences across primates in immune response strategies, including relative proportions of immune cell types and whether adaptive or innate responses are favored. It remains unclear which taxonomic level best explains variation in primate immune response strategies. Identifying this is important for understanding when and why these differences evolved. This review synthesizes major recent findings in primate immunology, to connect them to more generalized research on immune response strategies and present hypotheses for future research, focusing on major methodologies in the field. We demonstrate that gaining a better understanding of the evolution of primate immunity has far-reaching implications for our understanding of the evolutionary past of humans, and for present-day global health.

Indexed as

Adaptive ImmunityImmunity, InnatePrimatesAnimalsBiological EvolutionHumans

Identifiers

PMID41131162
PMCPMC12705460

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.