Evidence map›Paper›PMID 41131158›Full record

ArticleScientific reports2025

Isolated lumbar extension exercise alone or in a multimodal program for low back pain and radiculopathy: a non-randomized controlled trial.

Bruno Domokos, Julia Domokos, Gustav Andersson, Stefan Mannel, Linda May Weigel, Horst Josef Koch, Birgit Wallmann-Sperlich, Christoph Raschka, Christoph Spang

Abstract readControlled Clinical Trial
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bruno DomokosInstitute for Sports Science, University of Würzburg, Würzburg, Germany. bruno.domokos@uni-wuerzburg.de.
Julia DomokosPrivate Orthopaedic Spine Center Dr. Alfen & Colleagues, Würzburg, Germany.
Gustav AnderssonDepartment of Medical and Translational Biology, Umeå University, Umeå, Sweden.
Stefan MannelInnovative Manual Therapy Mannel, Würzburg, Germany.
Linda May WeigelPrivate Orthopaedic Spine Center Dr. Alfen & Colleagues, Würzburg, Germany.
Horst Josef KochHeinrich-Braun-Klinikum, Zwickau, Germany.
Birgit Wallmann-SperlichIntegrative and Experimental Exercise Science and Training, Faculty of Human Science, Institute for Sports Science, University of Würzburg, Würzburg, Germany.
Christoph RaschkaInstitute for Sports Science, University of Würzburg, Würzburg, Germany.
Christoph SpangInstitute for Sports Science, University of Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isolated lumbar extension resistance exercise (ILEX) has been shown to effectively address chronic low back pain (LBP) and paraspinal deconditioning. However, its role within the widely recommended multimodal management approaches remains unclear. This study aimed to: (1) closely monitor the effects of ILEX throughout the course of a 16-weeks intervention, applied as a stand-alone approach in patients with nociceptive and/or neuropathic pain and (2) to compare this intervention with a multimodal treatment program including general exercise (GE) and manual therapy (MT). Fifty-eight LBP patients were enrolled in this single-center (Wuerzburg, Germany), prospective, non-randomized controlled trial. The ILEX-only group (Powerspine Back [PSB]: n = 29) completed 25 sessions of ILEX, whereas the integrative group (PSB+ : n = 29) also received GE (added to each session) and MT (5 to 7 sessions). Outcome measures were assessed at baseline, 3, 6, 9 and 16 weeks including lumbar multifidus cross-sectional area (CSA), muscle thickness (MT), echointensity (EI) (ultrasound-derived), isometric lumbar strength (isokinetic device) and validated questionnaires (Visual Analog Scale [VAS]; Oswestry Disability Index [ODI]; Short-Form 36). Between-subjects repeated measures ANOVA and correlation analyses were performed. Both groups (PSB: m = 16, f = 15, Ø40.26 (± 13.71) years, BMI 25.16 (± 4.07) kg/m

Indexed as

Exercise TherapyLow Back PainRadiculopathyResistance TrainingAdultCombined Modality TherapyFemaleHumansLumbosacral RegionMaleMiddle AgedPain MeasurementProspective StudiesTreatment OutcomeDiagnostic imagingExercise therapyLow back painMuscle strengthRadiculopathyUltrasonography

Identifiers

PMID41131158
PMCPMC12550044

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.