Evidence map›Paper›PMID 41131156›Full record

ArticleScientific reports2025

A multi stage deep learning model for accurate segmentation and classification of breast lesions in mammography.

Sultan Ahmad, Eali Stephen Neal Joshua, Nakka Thirupathi Rao, Rania M Ghoniem, Belayneh Matebie Taye, Salil Bharany

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sultan AhmadDepartment of Computer Science, College of Computer Engineering and Sciences, Prince Sattam Bin Abdulaziz University, Alkharj, 11942, Saudi Arabia. s.alisher@psau.edu.sa.
Eali Stephen Neal JoshuaDepartment of Computer Science & Engineering, Gandhi Institute of Technology and Management (GITAM) (Deemed to be University), Visakhapatnam, Andhra Pradesh, India.
Nakka Thirupathi RaoDepartment of Computer Science & Engineering, Vignan's Institute of Information Technology (A), Visakhapatnam, 530049, Andhra Pradesh, India.
Rania M GhoniemDepartment of Information Technology, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.
Belayneh Matebie TayeDepartment of Computer Science, College of Informatics, University of Gondar, Gondar, Amhara, Ethiopia. belayneh.matebie@uog.edu.et.
Salil BharanyChitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, Punjab, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammography is a routine imaging technique used by radiologists to detect breast lesions, such as tumors and lumps. Precise lesion detection is critical for early treatment and diagnosis planning. Lesion detection and segmentation are still problematic due to inconsistencies in image quality and lesion properties. Hence, this work presents a new Multi-Stage Deep Lesion model (MSDLM) for enhancing the efficacy of breast lesion segmentation and classification. The suggested model is a Three-Unit Two-Parameter Gaussian model with U-Net, EfficientNetV2 B0, and a domain CNN classifier. U-Net is utilized for lesion segmentation, EfficientNetV2 B0 is employed for image deep feature extraction, and a CNN classifier is used for lesion classification. The MSDLM feature cascade is designed to enhance computational efficiency while retaining the most relevant features for breast cancer detection and identifying the minimum number of features most important in the detection and classification of breast lesions in mammograms. The Multi-Stage Deep Learning Model (MSDLM) was validated using two benchmark datasets, CBIS-DDSM and the Wisconsin breast cancer dataset. Segmentation and classification tasks were indicated by accuracy values of 97.6%, indicating reliability in breast lesion detection. Its sensitivity of 91.25% indicates its reliability in detecting positive cases, a basic requirement in medical diagnosis. It also indicated an Area Under the Curve (AUC) of 95.75%, indicating overall diagnostic performance irrespective of thresholds. The Intersection over Union (IoU) of 85.59% verifies its reliability to detect lesion areas in mammograms. MSDLM with a Gaussian distribution provides precise localization and classification of breast lesions. The MSDLM model allows for improved information flow and feature refinement. The algorithm outperforms baseline models in both effectiveness and computational cost. Its performance on two diverse datasets verifies its generalizability and enables radiologists to receive exact automated diagnoses.

Indexed as

Breast NeoplasmsDeep LearningImage Processing, Computer-AssistedMammographyAlgorithmsBreastFemaleHumansRadiographic Image Interpretation, Computer-AssistedROC CurveAccuracyBreast mass segmentationEfficientNetV2 B0GAU-NetGaussian distributionMammographySegmentationTransfer learningU-Net

Identifiers

PMID41131156
PMCPMC12549806

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.