Evidence map›Paper›PMID 41130991›Full record

ArticleNature communications2025

A cortex-wide multimodal microscope for simultaneous Ca

Wei Qin, Tingting Li, Linyang Li, Tian Jin, Baochen Li, Weizhi Qi, Yifan Chen, Haoyang Li, Shijie Ruan, Heng Guo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wei Qin *Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.ORCID http://orcid.org/0009-0001-0771-3324
Tingting Li *Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Linyang Li *Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Tian JinDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Baochen LiDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Weizhi QiDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Yifan ChenDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Haoyang LiDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Shijie RuanDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Heng GuoDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Xiao LiangDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Lei XiDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, China. xilei@sustech.edu.cn.ORCID http://orcid.org/0000-0002-2598-6801

Funding

National Natural Science Foundation of China (National Science Foundation of China) 61775028National Natural Science Foundation of China (National Science Foundation of China) 62022037National Natural Science Foundation of China (National Science Foundation of China) 62305148National Natural Science Foundation of China (National Science Foundation of China) 62435008National Natural Science Foundation of China (National Science Foundation of China) 62475110
6 · The paper itself

Abstract

Developments in optical imaging techniques have advanced the study of neurovascular coupling across the whole cortex. Unfortunately, each cortex-wide optical imaging modality is specialized in revealing limited neural or hemodynamic actions. Here, we develop a cortex-wide multimodal microscope (multiScope) integrating widefield Ca

Indexed as

CalciumCerebral CortexHemodynamicsMultimodal ImagingAnimalsLaser Speckle Contrast ImagingMaleMiceMice, Inbred C57BLMicroscopy, FluorescenceNeuronsNeurovascular CouplingPhotoacoustic TechniquesWakefulnessCalcium

Identifiers

PMID41130991
PMCPMC12550049

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.