Evidence map›Paper›PMID 41130797›Full record

ArticleLife science alliance2026

Mapping the structural dynamics of red- and blue-emitting beetle luciferases revealed by HDX-MS.

Abdul-Rahman Kharbatli, Juliana C Ferreira, Nathan M Lui, Rawdah Karwt, Shaolong Zhu, Liaqat Ali, Wael M Rabeh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdul-Rahman KharbatliScience Division, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID 0009-0002-9272-135X
Juliana C FerreiraScience Division, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
Nathan M LuiScience Division, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID 0000-0003-4950-0914
Rawdah KarwtDepartment of Genetics, Kazan Federal University, Kazan, Russia.ORCID 0000-0002-9770-8667
Shaolong ZhuDepartment of Chemistry, York University, Toronto, Canada.
Liaqat AliCore Technology Platforms, New York University Abu Dhabi, Saadiyat Campus, Abu Dhabi, United Arab Emirates.ORCID 0000-0001-6984-3012
Wael M RabehScience Division, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates wael.rabeh@nyu.edu.ORCID 0000-0001-6071-8581

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Beetle luciferases catalyze bioluminescent reactions using identical substrates-luciferin, ATP, and oxygen-yet emit colors ranging from green to red. As the luciferase fold is highly conserved, the structural basis of this spectral diversity remains elusive. Hydrogen/deuterium exchange mass spectrometry (HDX-MS) was used to systematically probe the conformational dynamics of green-emitting

Indexed as

ColeopteraHydrogen Deuterium Exchange-Mass SpectrometryLuciferasesAnimalsCatalytic DomainColorLuminescent MeasurementsProtein ConformationLuciferases

Identifiers

PMID41130797
PMCPMC12550276

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.