Evidence map›Paper›PMID 41130726›Full record

ArticleEnvironmental science & technology2025

Whole-Body Disposition and Metabolism of [

Yau Adamu, Nicole Marie Brandon, Andrea Adamcakova-Dodd, Hui Wang, Peter S Thorne

Abstract read
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yau AdamuHuman Toxicology Program, The University of Iowa, Iowa City, Iowa 52242, United States.ORCID 0000-0003-2388-1085
Nicole Marie BrandonDepartment of Occupational and Environmental Health, The University of Iowa, Iowa City, Iowa 52242, United States.
Andrea Adamcakova-DoddDepartment of Occupational and Environmental Health, The University of Iowa, Iowa City, Iowa 52242, United States.ORCID 0000-0002-0570-239X
Hui WangHuman Toxicology Program, The University of Iowa, Iowa City, Iowa 52242, United States.ORCID 0000-0002-5132-0077
Peter S ThorneHuman Toxicology Program, The University of Iowa, Iowa City, Iowa 52242, United States.ORCID 0000-0002-5045-0929

Funding

Training CoreP42ES013661 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 2006 to 2026
$60.3M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
NIEHS NIH HHS P30 ES005605NIEHS NIH HHS P42 ES013661
6 · The paper itself

Abstract

Toxicities of lower-chlorinated biphenyls (LC-PCBs) have drawn increasing attention due to growing evidence of their presence in school indoor air, with 2,4,4'-trichlorobiphenyl (PCB28) being a prevalent congener. The tissue levels and characteristics of individual PCB congeners determine the PCB toxicity. Yet, the tissue disposition time course of individual LC-PCBs following pulmonary exposure is largely unknown. To address this data gap, we investigated the whole-body disposition, metabolism, and elimination kinetics of PCB28 in rats following intratracheal lung dosing of radiolabeled [

Indexed as

LungPolychlorinated BiphenylsAnimalsCarbon RadioisotopesMaleRatsRats, Sprague-DawleyTissue Distribution2,4,4'-trichlorobiphenylCarbon RadioisotopesPolychlorinated BiphenylsADMEforever chemicalsPCB28polychlorinated biphenylpulmonarytoxicokinetics

Identifiers

PMID41130726
PMCPMC12593371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.