ArticleBMJ paediatrics open2025
Psychosocial and contextual risk factors of adolescent deliberate poisoning: a multicentre case-control study in Sri Lanka.
Article in BMJ paediatrics open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Factors Associated with Major PICU Interventions in Adolescents Hospitalized for Intentional Pharmaceutical Poisoning.Children (Basel, Switzerland) · 2026Article
- Analysis of risk factors for severe acute poisoning in children.Frontiers in pediatrics · 2026Article
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Authors and funding
7 authors.
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Abstract
introductionDeliberate self-poisoning is a leading method of self-harm among adolescents globally. This study aimed to identify psychosocial, familial and contextual risk factors associated with deliberate self-poisoning among Sri Lankan adolescents.
methodsA multicentre prospective case-control study was conducted across selected tertiary care hospitals in Sri Lanka over a 2-year period. Adolescents aged 10-17 years admitted with deliberate poisoning were recruited as cases. Age- and sex-matched controls were recruited from the same study settings. Structured interviews were conducted using a pretested tool assessing sociodemographic, psychological, family and school-related factors. Conditional logistic regression was used to estimate adjusted ORs (AORs) and 95% CIs.
resultsA total of 326 case-control pairs (n=652) were included. The majority of cases were female (74.5%) and aged 15-17 years. The most frequently ingested agents were paracetamol (45.1%) and oleander (10.7%). In multivariable analysis, personal history of psychiatric illness (AOR 2.76, 95% CI 1.92 to 5.41), previous self-injury (AOR 4.17, 95% CI 1.92 to 10.77), previous deliberate poisoning (AOR 4.02, 95% CI 2.86 to 5.19), non-heterosexual orientation (AOR 26.9, 95% CI 12.18 to 75.45), school dropout (AOR 4.01, 95% CI 2.06 to 6.57), home violence (AOR 8.93, 95% CI 3.27 to 26.47) and feeling depressed (AOR 2.08, 95% CI 1.49 to 3.20) were independently associated with deliberate poisoning.
conclusionDeliberate self-poisoning among Sri Lankan adolescents is strongly associated with psychiatric comorbidity, family adversity, sexual identity-related distress and school disengagement. These findings highlight the urgent need for integrated, adolescent-friendly mental health services, school-based screening and psychosocial support mechanisms.
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