Evidence map›Paper›PMID 41130276›Full record

Observational studyHomeopathy : the journal of the Faculty of Homeopathy2026

Enhancing Homeopathic Prescribing for Chronic Cough by Classifying the Reliability of Polar Symptoms.

Harleen Kaur, Lex Rutten, José E Eizayaga, Shalini Rao, Anurag Bajpai, Chetna Deep Lamba, Jyoti Sachdeva, Vinitha Er, Sonia Raizada, Rompicherla G R Kiranmayee and 12 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Homeopathy : the journal of the Faculty of Homeopathy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

22 authors.

Harleen KaurCentral Council for Research in Homoeopathy, New Delhi, India.
Lex RuttenIndependent Researcher, Breda, The Netherlands.
José E EizayagaDepartment of Homeopathy, Maimonides University, Buenos Aires, Argentina.
Shalini RaoCentral Council for Research in Homoeopathy, New Delhi, India.
Anurag BajpaiCentral Council for Research in Homoeopathy, New Delhi, India.
Chetna Deep LambaCentral Council for Research in Homoeopathy, New Delhi, India.
Jyoti SachdevaCentral Council for Research in Homoeopathy, New Delhi, India.
Vinitha ErNational Homoeopathy Research Institute in Mental Health (NHRIMH), Kottayam, Kerala, India.
Sonia RaizadaDr. D.P. Rastogi Central Research Institute (Homoeopathy), Noida, Uttar Pradesh, India.
Rompicherla G R KiranmayeeExtension Clinical Research Unit of DSU, Hyderabad, Andhra Pradesh, India.
Bodankar RajashekharRegional Research Institute for Homoeopathy, Gudivada, Krishna Dist., Andhra Pradesh, India.
Chittaranjan KunduDr. Anjali Chatterji Regional Research Institute of Homoeopathy, Kolkata, West Bengal, India.
Vaishali ShindeRegional Research Institute (Homoeopathy), Navi Mumbai, Maharashtra, India.
Sujata ChoudhuryRegional Research Institute (H), Puri, Odisha, India.
Amulya Ratna SahooDrug Proving Unit, Dr. Abhin Chandra Homoeopathic Medical College and Hospital, Unit-III, Bhubaneswar, Odisha, India.
Ratan Chandra ShilRegional Research Institute for Homoeopathy, Agartala, Tripura, India.
Abhijit ChakmaDr. Anjali Chatterji Regional Research Institute of Homoeopathy, Kolkata, West Bengal, India.
Nidhi MahajanCentral Research Institute for Homoeopathy, MPK Homoeo Medical College, Jaipur, Rajasthan, India.
Alok MishraDr. Anjali Chatterji Regional Research Institute of Homoeopathy, Kolkata, West Bengal, India.
Anil KhuranaCentral Council for Research in Homoeopathy, New Delhi, India.
Praveen OberaiCentral Council for Research in Homoeopathy, New Delhi, India.
Raj K ManchandaCentral Council for Research in Homoeopathy, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Assessment of relationship between polar symptoms (PS), such as weather, activity or food, and homeopathic medicines in chronic cough has produced some confusing outcomes. Statistical variation in the data partly explains the seemingly conflicting outcomes in prognostic factor research (PFR) of PS. Classification of statistical probability and selection of statistically reliable data can reduce conflicting outcomes. Objective: To make an inventory of statistically reliable PS and their relationship with homeopathic medicines in chronic cough. Methods: A prospective observational cohort study was conducted at 10 outpatient centers of the Central Council for Research in Homoeopathy, India. Patients with chronic cough were followed for 12 months. Effect of treatment was assessed using the ORIDL (Outcome in Relation to Impact on Daily Living) instrument, with symptom severity and health status evaluated respectively via the Cough Severity Index and EuroQoL 5D-5L. Prevalence and likelihood ratios (LRs) of PS were calculated for general and medicine-specific populations. Cumulative binomial probability (CBP) was used to determine whether symptom prevalence among good responders to specific medicines significantly differed from that of the general population. Results: Some LRs were unexpectedly low, which could be explained by asymmetry of frequency distributions, resulting in high prevalence of one symptom pole. CBP for homeopathic medicines was subsequently performed, with 131 symptoms classified as 'certain' or 'probable': 21 symptoms for Conclusion: Conflicting outcomes in PFR of PS can partly be explained by statistical variation. A classification of reliability was not feasible when expressed using the classical 95% confidence interval but could be achieved by CBP, resulting in certain and probable PS for 10 medicines. We still need clinical expertise and corroboration for future research. Practitioners need scientific training to prevent bias and use research instruments such as Likert scales and questionnaires.

Indexed as

Chronic CoughHomeopathyAdultFemaleHumansIndiaMaleMiddle AgedProspective StudiesReproducibility of ResultsSeverity of Illness Index

Identifiers

PMID41130276
PMCPMC13412703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.