Evidence map›Paper›PMID 41130164›Full record

ArticlePublic health2025

Knowledge that HPV can cause oropharyngeal cancer and cervical cancer among adults in the United States: A comparison of prevalence and predictors.

Iriana Peña-Manrique, Beth J Maclin, Aimée R Kreimer, Hosam Alraqiq, Alessandro Villa, Danping Liu, Siddharth Roy, Erica S Stephens, Loretto J Carvajal, Jaimie Z Shing

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Iriana Peña-ManriqueDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA; National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.
Beth J MaclinDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Aimée R KreimerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Hosam AlraqiqNational Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.
Alessandro VillaOral Medicine and Oral Oncology, Miami Cancer Institute. Baptist Health South Florida, Miami, FL, USA.
Danping LiuDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Siddharth RoyDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Erica S StephensDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Loretto J CarvajalDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA; Agencia Costarricense de Investigaciones Biomédicas (ACIB), Formerly Proyecto Epidemiológico Guanacaste, Fundación INCIENSA, San José, Costa Rica.
Jaimie Z ShingDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: Jaimie.Shing@nih.gov.

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

objectivesTo compare prevalence and predictors of knowledge that human papillomavirus (HPV) can cause oropharyngeal cancer (OPC) and cervical cancer among U.S. adults. STUDY

designCross-sectional.

methodsUsing Health Information National Trends Survey-5 cycles 1-4 (2017-2020), we estimated weighted prevalence of knowledge that HPV can cause OPC and cervical cancer, overall and by sex. Predictors were identified using logistic regression adjusting for age, sex, race and ethnicity, and education.

resultsFemales vs. males had greater OPC knowledge (22.3 % vs. 17.1 %) [adjusted odds ratio (aOR) = 1.4; 95 % confidence interval (95 % CI) = 1.2-1.6] and cervical cancer knowledge (59.4 % vs. 40.0 %) (aOR = 2.6; 95 % CI = 2.2-3.0). Females with notably greater OPC knowledge were White vs. Black (aOR = 2.0; 95 % CI = 1.5-2.7), and had a college degree or higher vs. high school or less (aOR = 2.8; 95 % CI = 2.1-3.7). Males with greater OPC knowledge had a college degree or higher vs. high school or less (aOR = 3.1; 95 % CI = 2.2-4.4) and visited a provider 1-2 times within the past year (aOR = 1.7; 95 % CI = 1.1-2.6). Females with greater cervical cancer knowledge were White vs. Black (aOR = 2.1; 95 % CI = 1.6-2.6), had a college degree or higher vs. high school or less (aOR = 5.6; 95 % CI = 4.5-6.9), and visited a provider within the past year (aOR = 2.2; 95 % CI = 1.7-2.9). Males with greater cervical cancer knowledge were White vs. Black (aOR = 1.6; 95 % CI = 1.1-2.4), had at least $75,000 vs. $34,999 or less annual income (aOR = 1.8; 95 % CI = 1.3-2.4), had a college degree or higher vs. high school or less (aOR = 4.7; 95 % CI = 3.5-6.2), and visited a provider within the past year (aOR = 1.5; 95 % CI = 1.1-2.2).

conclusionsHPV-related cancer knowledge is limited, especially for OPC. Knowledge disparities exist across many social and healthcare engagement factors, emphasizing need for broader dissemination of HPV education.

Indexed as

Health Knowledge, Attitudes, PracticeOropharyngeal NeoplasmsPapillomavirus InfectionsUterine Cervical NeoplasmsAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPapillomaviridaePrevalenceUnited StatesYoung AdultCervical cancerHPV knowledgeHPV vaccineOropharyngeal cancer

Identifiers

PMID41130164
PMCPMC12614091

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.