ReviewPLoS pathogens2025
Persister cells in human fungal pathogens.
Review in PLoS pathogens, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Beyond antifungal susceptibility: molecular mechanisms, detection, and clinical implications of fungal heteroresistance.Molecular biology reports · 2026Review
- Bridging the "Valley of Death" in Antifungal Therapy: Next-Generation Biomimetic and Exosome-Inspired Nanocarriers for Invasive Candidiasis.Journal of fungi (Basel, Switzerland) · 2026Review
- Clinical significance of a possible route of transmission ofWorld journal of gastrointestinal pathophysiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Microbicidal persistence refers to the phenomenon whereby a subpopulation of microbial cells enters a dormant state to evade drug killing. This phenomenon is associated with antibiotic treatment failure in bacterial infections, and thus, the characteristics and mechanisms of bacterial persistence have been extensively studied. Despite significant evolutionary divergence, microbicidal persistence has also been observed in fungi. Notably, recent studies have demonstrated that fungal persistence can occur within the host and significantly impair the efficacy of fungicidal drugs. Given the extremely limited range of first-line fungicidal agents currently in use, improving our understanding of the shared and unique mechanisms of antifungal persistence in various fungal pathogens is of great clinical importance. This review summarizes recent advances in the study of antifungal persistence, covering conceptual definitions, measurement methods, and molecular mechanisms. It also discusses future research directions in this field.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.