ArticleObesity surgery2025
Sex-Specific Association Between Serum VitaminD and Health Status Among Chinese Obesity People: A Cross-Sectional Study.
Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundEmerging evidence indicates associations between serum vitamin D (VD) levels and metabolic profiles in obesity. This study aimed to investigate the relationship between VD and metabolic health and body composition, with a specific focus on exploring sex-specific differences.
methodsData were sourced from a cohort. A linear regression model was used to explore the relationship between VD and various health indicators. Consensus clustering algorithm (CCA) identified the potential subtypes in male and female obese populations. Dose-response relationship was determined using a restricted cubic spline (RCS) model. Mediation effects of metabolic indicators between VD and obesity subtypes were explored.
resultsA total of 1507 participants were included in this study. The linear regression model revealed an inverse relationship between VD and fasting blood glucose, HbA1c, triglycerides, and homeostatic model assessment for insulin resistance (HOMA-IR) in males. VD demonstrated a positive association with high-density lipoprotein cholesterol (HDL-C) in females. CCA identified two clusters, named unhealthy and relatively healthy obesity. RCS suggested that individuals with serum VD levels exceeding 37.7 and 30.0 μmol/mL were more likely to be relatively healthy obese in the male and female populations, respectively. For mediation analysis, HOMA-IR mediated 31% of VD's effect in males (β = - 0.049, 95% CI - 0.102, - 0.003), while HDL-C mediated 15.8% in females (β = - 0.022, 95% CI - 0.038, - 0.009).
conclusionsObese individuals exhibiting lower serum VD levels were associated with an unhealthy status, marked by adverse metabolic indicators and body composition.
Indexed as
Identifiers
41129060What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.