ArticleThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2025
Bilateral acute limb ischemia complicating incessant supraventricular arrhythmias in wolff-parkinson-white syndrome: evaluating thromboprophylaxis across multiple cardioversions.
Article in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute limb ischemia (ALI) is a severe complication in patients with structural heart disease and recurrent arrhythmias that often leads to significant morbidity and potential lifelong disability. The combination of arrhythmia, recurrent electrical shocks in patients with incessant supraventricular tachycardia (SVT), and structural heart abnormalities may increase the risk of thrombus formation and migration, raising questions about the role of thromboprophylaxis in such high-risk scenarios. CASE PRESENTATION: We present a 54-year-old female with Wolff-Parkinson-White (WPW) Syndrome and structural heart disease who was admitted with incessant SVT, complicated by several episodes of ventricular tachycardia (VT) and ventricular fibrillation (VF). Despite multiple unsynchronized cardioversions, the patient remained hemodynamically unstable. Echocardiography revealed a dilated left ventricle with reduced systolic function and an intracardiac thrombus. During hospitalization, she underwent over ten direct current (DC) shocks, exacerbating her thromboembolic risk. On day three of hospitalization, she developed severe pain in her right leg, progressing to signs of ALI. Doppler ultrasound and CT angiography confirmed thrombi in the abdominal aorta and lower extremities, supporting the diagnose of ALI Rutherford III dextra and ALI Rutherford IIA sinistra. Surgical thrombectomy and anticoagulation were initiated, but ALI progressed, necessitating above-knee amputation in her right leg. DISCUSSION: Thromboprophylaxis in patients with structural heart disease and incessant arrhythmia must be carefully assessed. Incessant SVT alone does not justify early anticoagulation, but coexisting cardiomyopathy and repeated cardioversions increase thromboembolic risk. Identifying the underlying cause of structural abnormalities is essential to guide treatment and prevent severe complications. Delayed anticoagulation in the presence of undetected thrombus may result in irreversible events such as limb loss due to ALI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.