SynthesisBrain structure & function2025
Extraversion and the resting brain: a coordinate-based meta-analysis of resting-state functional brain imaging studies.
Synthesis in Brain structure & function, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Neural Correlates of Extraversion and Trait Creativity: A Graph Theory-Based Whole-Brain Functional Network Modularity Analysis.Journal of Intelligence · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The personality trait of extraversion, which is characterized by an outward focus, has been the subject of considerable research because of its implications for personal development and well-being. Although the relationship between extraversion and brain function has been studied extensively, the findings from different studies are often contradictory and highly heterogeneous. To address these inconsistencies, our study used a meta-analysis technique that included 19 resting-state functional neuroimaging studies (1440 healthy subjects, 116 peak coordinates). Our results revealed consistent positive correlations between extraversion and intrinsic activity within specific brain regions, including the left paracentral lobule extending into the inferior parietal lobule, the right lingual gyrus, and the right supplementary motor area. Conversely, we observed a negative correlation between extraversion and activity in the right superior and middle frontal gyrus. In addition, our analysis demonstrated that the link between extraversion and activation in the right inferior frontal gyrus is influenced by gender. This comprehensive exploration of brain activity patterns associated with extraversion provides novel insights and may inform personalized interventions focusing on specific brain regions relevant to extraversion-related difficulties.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.