Evidence map›Paper›PMID 41128856›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2026

Addressing mental health challenges in clinical practice: a qualitative study to investigate perspectives of international mental health experts.

Melissa G Halil, Anissa Abi-Dargham, John H Krystal, David M Clark, Adrian P Mundt, Helen Herrman, Solomon Rataemane, Fritzi Weitzenegger, Isabel Dziobek, Andreas Heinz and 1 more

Abstract read
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Melissa G HalilDepartment of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Charité Campus Mitte (CCM), Charitéplatz 1, 10117, Berlin, Germany. melissa.halil@charite.de.
Anissa Abi-DarghamDepartment of Psychiatry and Behavioral Health, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA.
John H KrystalYale University School of Medicine, New Haven, CT, USA.
David M ClarkOxford Centre for Anxiety Disorders and Trauma (OxCADAT), Department of Experimental Psychology, The Old Rectory, University of Oxford, Paradise Square, Oxford, OX1 1TW, UK.
Adrian P MundtCentro de Investigación Biomédica, Medical Faculty, Universidad Diego Portales, Santiago, Chile.
Helen HerrmanOrygen and Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC, Australia.
Solomon RataemaneDepartment of Psychiatry, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South Africa.
Fritzi WeitzeneggerDepartment of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin (CBF), Berlin, Germany.
Isabel DziobekGerman Center for Mental Health (DZPG), Partner Site Berlin-Potsdam, Berlin, Germany.
Andreas HeinzDepartment of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), Medical School and University Hospital, Eberhard Karls University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0001-5405-9065
Irina BaskowDepartment of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, Charité Campus Mitte (CCM), Charitéplatz 1, 10117, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMental illnesses are not only associated with the highest level of subjective suffering compared to other chronic diseases but at the same time with a significantly increased morbidity. Especially in industrialized countries, a dramatically increasing proportion of sick leave and early retirement due to mental illness diagnoses is observed, pointing to increased social stress factors and a close association with societal changes and emphasizing challenges to the health care system. The following qualitative study was conducted as part of the establishment of the German Center for Mental Health, which unites excellence in psychiatric, psychological and neuroscientific research in Germany to facilitate translation of basic into clinical research and general health care.

methodsA 120-minute, guided, virtual focus group discussion was conducted with international experts in the field of mental health research from Chile, the USA, the UK, South Africa, and Australia to represent views from different continents. The participants discussed international trends, unrecognized needs and gaps in clinical practice and recognized many opportunities and challenges in the research of the different topics of the German Center for Mental Health. Furthermore, the focus areas of the German Center were presented, and participants were asked about the opportunities and challenges in researching these topics. The evaluation method was based on qualitative content analysis according to Mayring. The focus group discussion was transcribed and coded with MAXQDA 2022 software. The reliability of the coding was checked by using the intercoder reliability and Cohens Kappa.

resultsThe experts emphasized the high mortality due to comorbidity of somatic and mental disorders including addiction and called for a mechanism-based approach to promote individualized treatment. Furthermore, the impact of poverty, social exclusion, stigma and discrimination was addressed as a key modifiable environmental risk factor. The experts highlighted digital tools, computational models and AI based approaches for precision psychiatry. To systematically evaluate real-world outcomes, the experts emphasized the need for interdisciplinary research including behavioral, computational, social, and neurobiological scientists and experts by experience. DISCUSSION: This study highlights the need for interdisciplinary and participatory approaches in mental health research. Key challenges include the high comorbidity of mental and physical disorders, the impact of social determinants, and gaps in translating research into practice. Experts emphasized the importance of digital tools, computational psychiatry, and community-based interventions to enhance prevention and treatment. The German Center for Mental Health (DZPG) is well-positioned to address these challenges by integrating diverse expertise and fostering innovation in mental health care.

Indexed as

Attitude of Health PersonnelMental DisordersMental HealthFocus GroupsGermanyHumansQualitative ResearchFocus group studyGerman center for mental health (DZPG)Mental health researchPrecision psychiatrySocial determinants of mental healthTranslational psychiatry

Identifiers

PMID41128856
PMCPMC12904902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.