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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

EQ-5D-5L Iranian population norms derived from the local value set during the COVID-19 pandemic.

Somayeh Afshari, Thomas G Poder, Rajabali Daroudi, Ali Akbari Sari, Hosein Ameri

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

  1. Psychometric validation of a cognition and social participation bolt-on for the EQ-5D-5L in SARS-CoV-2 infected German healthcare workers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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5 · Who and what money

Authors and funding

5 authors.

Somayeh AfshariHealth Management and Economics Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran.
Thomas G PoderDepartement of management, evaluation, and health policy, School of Public Health, University of Montreal, Montreal, QC, Canada.
Rajabali DaroudiDepartment of Health Management, Policy, and Economics, School of Public Health, Tehran University of Medical Science, Tehran, Iran.
Ali Akbari SariDepartment of Health Management, Policy, and Economics, School of Public Health, Tehran University of Medical Science, Tehran, Iran. akbarisari@tums.ac.ir.
Hosein AmeriDepartement of management, evaluation, and health policy, School of Public Health, University of Montreal, Montreal, QC, Canada. hamery7@yahoo.com.ORCID http://orcid.org/0000-0002-9914-034X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo derive the first population norms from the EQ-5D-5L in Iran during the COVID-19 pandemic.

methodsData were obtained from a study conducted in Iran during the COVID-19 pandemic in 2021. Face-to-face, computer-assisted interviews were conducted in a single visit, involving respondents from diverse sociodemographic backgrounds and providing a balanced representation of age and gender groups. Normative data for the EQ-5D-5L dimensions, EQ-5D-5L index values, and EuroQol visual analogue scale (EQ-VAS) scores were summarized by dimensions and disaggregated by age groups and gender. Multivariable logistic and Tobit regression models were used to investigate the associations between participants' sociodemographic characteristics and their self-reported health, as measured by the EQ-5D-5L instrument, including responses on the five dimensions, EQ-5D-5L index values, and EQ-VAS scores.

resultsAmong 1,004 participants, the mean index value and EQ-VAS score were 0.832 and 78.27, respectively. Full health was reported in 37.65% (EQ-5D-5L) and 6.18% EQ-VAS of participants. Anxiety/depression (AD) was the most frequently reported problem (47%), followed by pain/discomfort (36%). EQ-5D-5L index values and EQ-VAS scores decreased with age and increased with education, while women reported slightly worse health states than men. Multivariable logistic regressions showed that men had higher odds of reporting problems in most dimensions except in AD. Students had the lowest odds of reporting problems, whereas divorced individuals had the highest. Age, education, marital status, employment, and chronic illness were significantly associated with EQ-5D-5L index values and EQ-VAS scores (P < 0.001).

conclusionEQ-5D-5L index values and EQ-VAS scores were associated with age, educational level, marital status, employment status, and the presence of chronic illness. These norms provide valuable insights to support health funders and policymakers in making informed decisions about resource allocation.

Indexed as

COVID-19Health StatusQuality of LifeAdolescentAdultAgedFemaleHumansIranMaleMiddle AgedPandemicsSARS-CoV-2Surveys and QuestionnairesYoung AdultEQ-5D-5LEQ-VASGeneral populationHealth utilitiesIranPopulation norms

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.