Evidence map›Paper›PMID 41128814›Full record

ArticleEpilepsia open2025

Reply to Letter to the Editor regarding the article "SCN1A gain of function effects in Dravet syndrome: Insights into clinical phenotypes and therapeutic implications".

Yoko Kobayashi Takahashi, Kenshiro Tabata, Shimpei Baba, Eri Takeshita, Noriko Sumitomo, Yuko Shimizu-Motohashi, Takashi Saito, Eiji Nakagawa, Atsushi Ishii, Shinichi Hirose and 4 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsia open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yoko Kobayashi TakahashiDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6235-4184
Kenshiro TabataDepartment of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.
Shimpei BabaDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.ORCID https://orcid.org/0000-0002-0596-3338
Eri TakeshitaDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
Noriko SumitomoDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
Yuko Shimizu-MotohashiDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
Takashi SaitoDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8253-7906
Eiji NakagawaDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.ORCID https://orcid.org/0000-0002-9285-4550
Atsushi IshiiDepartment of Neurology, University of Arizona, Tucson, Arizona, USA.
Shinichi HiroseGeneral Medical Research Center, School of Medicine, Fukuoka University, Fukuoka, Japan.
Mitsuhiro KatoDepartment of Pediatrics, Showa Medical University School of Medicine, Tokyo, Japan.
Naomichi MatsumotoDepartment of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Japan.ORCID https://orcid.org/0000-0001-9846-6500
Hirofumi KomakiDepartment of Child Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.
Ken InoueDepartment of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.

Funding

Japan Agency for Medical Research and Development JP24ek0109617Japan Agency for Medical Research and Development JP24ek0109648Japan Agency for Medical Research and Development JP24ek0109674Japan Agency for Medical Research and Development JP24ek0109677Japan Agency for Medical Research and Development JP24ek0109760Japan Society for the Promotion of Science JP24K02230National Center of Neurology and PsychiatryTakeda Science Foundation
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41128814
PMCPMC12716295

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.