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Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Preoperative care through aromatherapy and music therapy: comparative study on anxiety and physiological indices in mastectomy candidates.

Faezeh Samadi, Nasim Aminaie Chatroodi, Shima Haghani, Seyed Rouhollah Miri, Alireza Abdollahi, Esmaeil Mohammadnejad

Abstract readRandomized Controlled TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Faezeh SamadiDepartment of Medical-Surgical Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
Nasim Aminaie ChatroodiDepartment of Medical-Surgical Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
Shima HaghaniNursing and Midwifery Care Research Center, Health Management Research Institute, Iran University of Medical Sciences, Tehran, Iran.
Seyed Rouhollah MiriDepartment of Surgical Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Alireza AbdollahiDepartment of Pathology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Esmaeil MohammadnejadDepartment of Medical-Surgical Nursing, Research Center for Antibiotic Stewardship and Antimicrobial Resistance, Tehran University of Medical Sciences, Tehran, 1419733171, Iran. emohammadnejad@sina.tums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePreoperative anxiety is a significant concern, particularly among women undergoing procedures that may alter body image, such as a mastectomy. If untreated, this anxiety can lead to complications, underscoring its importance in preoperative care. Identifying nursing interventions with minimal side effects is crucial, given the potential of modern treatments to exacerbate anxiety. Therefore, this study aims to determine and compare the effect of aromatherapy and music therapy on physiological indices and preoperative anxiety of female mastectomy candidates.

methodsA three-group randomized clinical trial was conducted on 99 female mastectomy candidates at the Cancer Institute of Imam Hospital, Tehran. Participants were selected using convenience sampling and randomly assigned to aromatherapy, music therapy, or control groups. The intervention included 30 min of receptive music therapy using selected pieces or inhalation aromatherapy with Damask rose, while the control group received usual nursing care. Anxiety levels were measured using the NVAAS scale and physiological indicators, including vital signs and salivary cortisol, before and 10 min after the intervention. Data analysis was performed using SPSS version 16.

resultsThe findings of this research show that all groups experienced an improvement in anxiety scores, but the impact of the two intervention groups was more significant and effective (p < 0.001). Alterations in physiological indices showed no statistically significant difference in the control group (p > 0.05). Physiological indices variations, except SpO

conclusionThis study demonstrated that the use of two complementary medicine approaches, inhalation aromatherapy and receptive music therapy, can be effective in reducing preoperative anxiety in patients and improving physiological indices. Employing such noninvasive approaches with minimal side effects and favorable for patients in clinical settings is recommended.

trial registrationClinicalTrials.gov Identifier: IRCT20230221057482N1.

Indexed as

AnxietyAromatherapyBreast NeoplasmsMastectomyMusic TherapyPreoperative CareAdultAgedFemaleHumansIranMiddle AgedAromatherapyMastectomyMusic therapyPreoperative anxiety

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.