ArticleJACC. Case reports2025
Aortic Bioprosthetic Stenosis Leading to Heyde Syndrome.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association of red cell distribution width and lymphocyte count with the presence and severity of calcific aortic valve stenosis.Journal of cardiothoracic surgery · 2026Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHeyde syndrome (HS) is the constellation of aortic stenosis and gastrointestinal bleeding due to arteriovenous malformation (AVM). CASE SUMMARY: A 74-year old man presented with angina, dyspnea, and fatigue. His work-up was pertinent for significant anemia, severe bioprosthetic aortic stenosis, and a duodenal AVM. The patient required blood transfusions and AVM clipping. He was diagnosed with bioprosthetic HS and referred to the cardiology team for transcatheter aortic valve replacement consideration. DISCUSSION: Reports of bioprosthetic HS are scarce in the literature. This case report describes the investigation and management of HS amid recurrent anemic episodes and diagnostic uncertainty. TAKE-HOME MESSAGES: Recurrent episodes of idiopathic anemia in patients with a prosthetic valve should raise concern for HS. Clinicians with a high suspicion of HS and negative esophagogastroduodenoscopy/colonoscopy should pursue capsule endoscopy or push enteroscopy to fully assess the small bowel. A normal von Willebrand factor in isolation should not rule out HS.
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