Evidence map›Paper›PMID 41128352›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2026

A multifaceted approach to advancing data quality and fitness standards in multi-institutional networks.

Hanieh Razzaghi, Kimberley Dickinson, Kaleigh Wieand, Samuel Boss, Hunter Weidlich, Yungui Huang, Keith Morse, Sujan Kumar Mutyala, Jyothi Priya Alekapatti Nandagopal, Karthik Viswanathan and 2 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hanieh RazzaghiApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.
Kimberley DickinsonApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.
Kaleigh WieandApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.ORCID 0009-0003-7477-2601
Samuel BossApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.
Hunter WeidlichApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.
Yungui HuangIT Research and Innovation, Nationwide Children's Hospital, Columbus, OH 43205, United States.
Keith MorseDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, United States.
Sujan Kumar MutyalaInformation Services, Texas Children's Hospital, Houston, TX 77030, United States.
Jyothi Priya Alekapatti NandagopalIS Research Data & Technology Services, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, United States.
Karthik ViswanathanBiomedical Research Informatics Center, Nemours Children's Hospital, Wilmington, DE 19803, United States.
Christopher B ForrestApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.ORCID 0000-0003-1252-068X
L Charles BaileyApplied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.ORCID 0000-0002-8967-0662

Funding

NIHNIH HHS OT2HL161847-01PCORI HHS ME-2020C3-21199PCORI HHS RI-CHOP-01-PS1PEDSnet infrastructure, PCORI ME-2020C3-21199Researching COVID to Enhance Recovery
6 · The paper itself

Abstract

objectiveTo construct a data quality (DQ) system that incorporates combinations of methods to evaluate data characteristics and analytic fitness across research questions for multiple uses. MATERIALS AND

methodsDrawing from experience of other data quality programs, network data extraction needs, and recurring study requirements, we developed 5 standards to guide development of a modular, multifaceted data quality system. These included annotation and documentation, ability to measure research readiness, reproducibility across networks, flexibility for the user, and interpretability to research and project teams. Implementation of checks based on these principles focused on reusability and interactive visualization of results.

resultsWe identified 10 check types producing over 444 check applications and deployed them in 2 multi-institutional networks. Check types span structural conformance to a data model, utility for common research needs, and study-specific customization. All check types are customizable without dependencies between them. A dashboard visualizes results, permitting adjustments based on number of data sources, need for source masking, and the user's focus. All components can be applied as written to any data source using OMOP and are readily modified for other data models. DISCUSSION: We have extended previous work through our novel and multifaceted approach to data quality assessment, addressing needs in both network data improvement and research usage. We developed a capable and deployable system rather than tailoring to specific use cases.

conclusionOur novel DQ assessment system provides essential components for future standardization and collaboration to improve fitness of clinical data for intended use.

Indexed as

Data Accuracyclinical research networksdata qualityelectronic health recordslearning health systemsmulti-institutional research

Identifiers

PMID41128352
PMCPMC12844579

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.