Evidence map›Paper›PMID 41128283›Full record

ArticleAngewandte Chemie (International ed. in English)2025

Facile (Z)-Selective Synthesis of β,γ-Unsaturated Ketones by a Silicon-based Olefination Strategy.

Daniya Aynetdinova, Jakub Brześkiewicz, Nikolaos Skoulikas, Nuno Maulide

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniya Aynetdinova *Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, Vienna, Austria.
Jakub Brześkiewicz *Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, Vienna, Austria.
Nikolaos Skoulikas *Institute of Organic Chemistry, University of Vienna, Währinger Straße 38, Vienna, Austria.
Nuno MaulideInstitute of Organic Chemistry, University of Vienna, Währinger Straße 38, Vienna, Austria.ORCID https://orcid.org/0000-0003-3643-0718

Funding

Austrian Science Fund ESP5366524Austrian Science Fund P37182European Union 101142915Polish National Agency for Academic Exchange
6 · The paper itself

Abstract

A novel silicon-based olefination strategy to access challenging β,γ-(Z)-unsaturated ketones with high diastereoselectivity in a single step from easily accessible, branched vinyl silanes is presented. This new disconnection resolves many longstanding challenges that have prevented general and efficient synthetic approaches to (Z)-deconjugated enones, affording a broad scope of this type of alkenes with high functional group tolerance. The developed transformation has been applied as a key step in the synthesis of a range of natural products.

Indexed as

Charge relocationVinyl silanes(Z)‐Selective olefination

Identifiers

PMID41128283
PMCPMC12668309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.