Trial reportJournal of the American Heart Association2025
Early-Life Sociodemographic Factors and Cardiovascular Health in Preadolescence Among Low-Income and Racially and Ethnically Diverse Children.
Trial report in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01606891 (Linking Primary Care, Communities and Families to Prevent Obesity Among Preschoolers), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Linking Primary Care, Communities and Families to Prevent Obesity Among Preschoolers
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study examined the relationship between early childhood sociodemographic factors, a subset of social determinants of health, and preadolescent cardiovascular health (CVH) among a cohort of children from low-income and racially and ethnically diverse households using the American Heart Association Life's Essential 8 (except sleep).
methodsThis secondary data analysis used data from the NET-Works (Now Everybody Together for Amazing and Healthful Kids) randomized controlled trial and NET-Works 2 at the U follow-up study. Children (n=268) were 2 to 4 years at enrollment and followed through preadolescence (7-11 years). Sociodemographic factors at baseline were exposures. The main outcome was the CVH score (high (≥80) versus lower (<80)), calculated using Life's Essential 8 factors measured at preadolescence. Modified Poisson regression models estimated risk ratios (RRs) and 95% CIs for the association between sociodemographic factors and CVH.
resultsIn early childhood, living in households with an annual income of $35 000 to $64 999 (relative to <$15 000) (RR, 2.01 [95% CI, 1.3-3.0]), a parent with at least a bachelor's degree (RR, 2.1 [95% CI, 1.3-3.3]), enrollment in social security, disability, or unemployment (RR, 1.6 [95% CI, 1.0-2.4]), and Non-Hispanic White (RR, 2.2 [95% CI, 1.5-3.3]) were associated with high CVH in preadolescence. Among Life's Essential 8 factors, lower body mass index percentile and cholesterol, and higher physical activity levels and diet quality were most strongly associated with high CVH scores.
conclusionsEarly-life disadvantaged sociodemographic factors were negatively associated with preadolescent CVH among children from low-income and racially and ethnically diverse households. Current public health prevention efforts to alleviate social disadvantage in early childhood are insufficient for long-term CVH. REGISTRATION: URL: https://clinicaltrials.gov; Unique identifier: NCT01606891.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.