SynthesisJournal of cosmetic dermatology2025
Enhancing Dermal Absorption of Cosmeceuticals: Innovations and Techniques for Targeted Skin Delivery.
Synthesis in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Enhancing Dermal Absorption of Cosmeceuticals: Innovations and Techniques for Targeted Skin Delivery.Journal of cosmetic dermatology · 2025Pooled it
- Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae-An overview towards application in cosmetics.International journal of cosmetic science · 2026Review
- Phytochemical Profiling and Computational Screening ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Nanotechnology-based drug formulation and delivery systems for skin medical aesthetic dermatology: mechanisms, applications, and safety.Frontiers in pharmacology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundAs beauty consumption upgrades and skincare concepts evolve toward science-backed efficacy, the field of cosmetology has put forward higher requirements for the dermal absorption efficiency of efficacious products. Notably, amid the global medical aesthetics market's 12.8% Compound Annual Growth Rate (projected to reach $35,327.5 million by 2030), rising demand for high-efficacy cosmeceuticals has amplified the significance of a longstanding issue: the low transdermal efficiency of active ingredients due to skin barrier and molecular constraints. Various studies have explored different dermal absorption promotion methods, but there is a lack of a systematic review that encompasses all types of permeation promotion technologies.
aimsThis review aims to systematically sort out the mechanism of dermal absorption and comprehensively summarize the commonly used permeation methods, in order to provide technical solutions for breaking through the barriers of active ingredient delivery and realizing the targeting effect of the skin in the deep layers of the skin.
methodsWe conducted a comprehensive review and analysis of existing literature related to dermal absorption promotion methods, systematically organizing the mechanisms of dermal absorption and integrating the commonly used permeation approaches.
resultsActive ingredients show low transdermal efficiency due to skin barrier and molecular constraints, with permeation via epidermal pathways and appendages. Non-invasive (chemical enhancers, nanocarriers, ultrasound) and invasive (microneedles, electroporation, needle-free injectors) techniques exist, with combinations boosting efficacy.
conclusionsAppropriate dermal technology is crucial to solve the problem of low dermal efficiency of active ingredients. The systematic sorting of dermal absorption mechanisms and the comprehensive summary of commonly used permeation methods in this review can provide effective technical support for the development of high-efficacy cosmeceuticals and the improvement of dermal penetration efficiency in the field of cosmetology.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.