Evidence map›Paper›PMID 41127936›Full record

ArticleAutism research : official journal of the International Society for Autism Research2025

Specific Association Patterns Between Brain Glutathione Levels, Myelination, and Functional Connectivity in Adults With Autism Spectrum Disorder.

Toshiki Iwabuchi, Takaharu Hirai, Naoko Umeda, Hideto Yogo, Yuuta Nishimiya, Yuuki Nishigaki, Masaru Watanabe, Hidenori Yamasue, Masatsugu Tsujii, Kenji J Tsuchiya and 1 more

Abstract read
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In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Toshiki IwabuchiResearch Center for Child Mental Development, Hamamatsu University School of Medicine, Shizuoka, Japan.ORCID 0000-0003-1747-8222
Takaharu HiraiDepartment of Psychiatric and Mental Health Nursing, School of Nursing, University of Fukui, Fukui, Japan.ORCID 0000-0002-3307-8109
Naoko UmedaLife Science Innovation Center, University of Fukui, Fukui, Japan.
Hideto YogoKojin Hospital, Nagoya, Aichi, Japan.
Yuuta NishimiyaKojin Hospital, Nagoya, Aichi, Japan.
Yuuki NishigakiKojin Hospital, Nagoya, Aichi, Japan.
Masaru WatanabeKojin Hospital, Nagoya, Aichi, Japan.
Hidenori YamasueUnited Graduate School of Child Development, The University of Osaka, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Osaka, Japan.
Masatsugu TsujiiSchool of Contemporary Sociology, Chukyo University, Nagoya, Aichi, Japan.
Kenji J TsuchiyaResearch Center for Child Mental Development, Hamamatsu University School of Medicine, Shizuoka, Japan.
Hideo MatsuzakiUnited Graduate School of Child Development, The University of Osaka, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Osaka, Japan.ORCID 0000-0002-6869-1261

Funding

Japan Society for the Promotion of Science 19K14175Japan Society for the Promotion of Science 22K02405Japan Society for the Promotion of Science 23K27527
6 · The paper itself

Abstract

Recent studies have implicated oxidative stress in the pathophysiology of autism spectrum disorder (ASD). Postmortem brain studies have revealed decreased levels of the reduced form of glutathione (GSH), an important antioxidant, in some brain regions in individuals with ASD; however, in vivo evidence is lacking. Using proton magnetic resonance spectroscopy, T

Indexed as

Autism Spectrum DisorderBrainGlutathioneMyelin SheathAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleNeural PathwaysYoung AdultGlutathioneautism spectrum disorderglutathionemagnetic resonance spectroscopymyelin mapresting‐state functional connectivity

Identifiers

PMID41127936
PMCPMC12729515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.