Evidence map›Paper›PMID 41127777›Full record

ReviewCureus2025

The Prognostic Indicators of Progression From Solitary Plasmacytoma to Multiple Myeloma: A Narrative Review.

Jeremy I Purow, Alejandra Viera, Shaun M Crist, Melissa Ruprich, Stephanie Ocejo, Joanna Herrera, Peter P Wahba, Marco Ruiz-Andia

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Aggressive mediastinal amyloidosis mimicking malignancy: a case report.International journal of surgery case reports · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeremy I PurowOncology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Alejandra VieraOncology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Shaun M CristOncology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Melissa RuprichOncology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Stephanie OcejoOncology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Joanna HerreraOncology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Peter P WahbaOncology, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Marco Ruiz-AndiaMalignant Hematology/Bone Marrow Transplant/HIV Oncology, Miami Cancer Institute, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solitary plasmacytomas (SPs), encompassing both solitary bone plasmacytoma (SBP) and extramedullary plasmacytoma (EMP), are rare plasma cell neoplasms that carry a risk of progression to multiple myeloma (MM). This review synthesizes current literature on the prognostic indicators predictive of such progression. High-risk cytogenetic abnormalities have been consistently linked to faster transition to MM. Other factors, such as tumor size, age, and persistent M-protein levels after treatment, are also prognostic factors. While radiotherapy remains the cornerstone of treatment, its curative potential is influenced by these indicators. Time to progression to MM is highly variable. This review highlights the need for standardized risk stratification systems to guide surveillance and treatment decisions in patients with SP.

Indexed as

abnormal plasma cellsbiomarkerscytogenetic abnormalitiesmultiple myelomaplasmacytoma

Identifiers

PMID41127777
PMCPMC12539537

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.