Evidence map›Paper›PMID 41127769›Full record

ArticleCureus2025

Clinical Relevance of Initial Hounsfield Unit Values in Predicting Outcomes and Complications of Aneurysmal Subarachnoid Hemorrhage.

Yushin Takemoto, Yu Hasegawa, Kozo Tashima, Akihito Hashiguchi, Koichi Moroki, Hajime Tokuda, Akitake Mukasa

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yushin TakemotoNeurosurgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, JPN.
Yu HasegawaNeurosurgery, Ariakeseijin Hospital, Kumamoto, JPN.
Kozo TashimaNeurosurgery, Tokuda Neurosurgical Hospital, Kanoya, JPN.
Akihito HashiguchiNeurosurgery, Tokuda Neurosurgical Hospital, Kanoya, JPN.
Koichi MorokiNeurosurgery, Tokuda Neurosurgical Hospital, Kanoya, JPN.
Hajime TokudaNeurosurgery, Tokuda Neurosurgical Hospital, Kanoya, JPN.
Akitake MukasaNeurosurgery, Kumamoto University Hospital, Kumamoto, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to evaluate whether the initial Hounsfield unit value (IT-HUV), easily obtained from non-contrast CT, serves as a reliable predictor not only for symptomatic vasospasm (SVS) but also for delayed cerebral ischemia (DCI) and overall prognosis in patients with aneurysmal subarachnoid hemorrhage (SAH). METHODOLOGY: A retrospective cohort of 95 patients with aneurysmal SAH who underwent craniotomy clipping and completed rehabilitation between January 2010 and December 2019 was analyzed. Associations between radiological parameters and functional outcomes (modified Rankin Scale (mRS)), as well as DCI and SVS, were assessed using univariate and multivariate analyses.

resultsOf the included patients, 27 (28.4%) had poor outcomes (mRS 4-5), 20 (21.1%) developed DCI, and 19 (20%) experienced SVS. Significant correlations were observed between IT-HUV and mRS (

conclusionsIT-HUV provides a practical and reliable imaging biomarker for predicting prognosis, DCI, and SVS in patients with aneurysmal SAH. Incorporating IT-HUV into routine assessments may enhance risk stratification and guide individualized treatment strategies.

Indexed as

aneurysmal subarachnoid hemorrhagecomputed tomographydelayed cerebral ischemiahounsfield unit valueinterpeduncular cisternprognostic markersymptomatic vasospasm

Identifiers

PMID41127769
PMCPMC12539850

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