ArticleCureus2025
Tenosynovial Giant Cell Tumors in the Hand and Foot.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
backgroundGiant cell tumor of the tendon sheath (GCTTS) is one of the most common benign, slow-growing soft tissue tumors of the hand and foot. This study aimed to evaluate the anatomic distribution of the GCTTS and correlate the surgical treatment with clinical outcomes and recurrence rates.
methodsIn this retrospective study, a total of 78 cases of GCTTS of the hand and foot operated from January 1, 2003 to December 31, 2020, with anatomopathological confirmation of diagnosis, were included. Patients were investigated with plain radiographs of the involved anatomic area and magnetic resonance imaging (MRI). All tumors were excised under regional anesthesia, tourniquet control, and magnifying loupes.
resultsThe most frequent symptom at admission was a painless, mobile, and lobulated subcutaneous mass, which gradually increased in size. The average time period between the onset of the symptoms and the clinical evaluation was 5.6 months. The study contained 30 male and 48 female patients, and the average age was 46.31 years. The tumor was located on the upper extremity in the majority of cases (92.3%) with a 12:1 hand-to-foot proportion. Of the lesions, 22.23% were located in the thumb, 20.82% in the second digit, 16.75% in the third digit, 11.12% in the fourth digit, and 20.82% in the fifth digit. Around 50% of foot lesions were located in the hallux. According to the pathology reports, the mean dimension of hand tumors was 1.2 cm at the greatest axis, and of the foot tumors, it was 3.3 cm. There was no significant correlation between the anatomic distribution of GCTTS, gender, age, size of the tumor, and recurrence rates. Recurrence was noted in five cases (6.4%).
conclusionAccurate imaging of GCTTS with MRI and plain radiographs, followed by radical excision of the lesion, is fundamental for minimizing recurrence potential, which should be underlined to the patient.
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