ReviewCureus2025
A Systematic Review on Whether Retinal Artery Microaneurysms Are Reliable Predictors of Coronary Artery Disease Severity.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronary artery disease (CAD) remains one of the leading causes of mortality in the UK. The growing and ageing population has led to increasing CAD prevalence and escalating healthcare costs. Current diagnostic tools like coronary angiography are too invasive for large population-level screening. Retinal artery microaneurysms (RAMs) are caused by microvascular damage and are detectable via non-invasive eye screening. This raises the possibility of a novel screening tool to help identify individuals at risk of CAD. This systematic review investigates whether RAMs are a reliable predictor of CAD severity. A Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA)-compliant approach was used in the review, and eligible studies were selected. Preliminary evidence suggests that RAMs may serve as a non-invasive indicator of CAD severity, enabling more non-invasive approaches in helping cardiovascular risk stratification of the general population. Integration of retinal imaging into cardiovascular risk assessment protocols could hold promise for the future of preventative cardiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.