ReviewCureus2025
Central Retinal Artery Occlusion in Acute Care: Current Practices and Emerging Therapies.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Special Issue "Ocular Ischemic Diseases: From Molecular Mechanisms to Therapeutics".International journal of molecular sciences · 2026Article
- Central Retinal Artery Occlusion Following Cosmetic Blepharoplasty in a Young Patient: A Case Report.Case reports in ophthalmological medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central retinal artery occlusion (CRAO) represents a critical ophthalmological emergency characterized by sudden, painless monocular vision loss and requires immediate intervention within emergency department settings. This narrative review examines the current evidence regarding CRAO management, emphasizing its pathophysiology, risk factors, clinical presentation, diagnostic approaches, and therapeutic interventions. The condition's complex etiology encompasses both embolic and inflammatory processes, with significant associations to cardiovascular risk factors and systemic diseases. Despite its critical nature, CRAO management faces substantial challenges, including delayed patient presentation, limited therapeutic windows, and the absence of universally accepted treatment protocols. Current diagnostic approaches incorporate traditional fundoscopic examination alongside emerging technologies such as point-of-care ultrasound and optical coherence tomography. While conventional management strategies include ocular massage, intraocular pressure reduction, and systemic therapies, their efficacy remains limited by insufficient evidence from randomized controlled trials. Emerging therapeutic approaches, including targeted thrombolysis, hyperbaric oxygen therapy, and novel surgical interventions, show promise but require further investigation. The review emphasizes the importance of a multidisciplinary approach involving emergency medicine, ophthalmology, and neurology specialists to optimize patient outcomes. Future directions highlight the potential of artificial intelligence-assisted diagnostics, standardized "eye stroke" protocols, and ongoing research into novel therapeutic interventions. Success in addressing these challenges requires continued investigation through rigorous clinical trials, improved public awareness regarding CRAO symptoms, and enhanced emergency department protocols to facilitate rapid diagnosis and treatment initiation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.