Evidence map›Paper›PMID 41127686›Full record

ArticleClinical case reports2025

Immune-Mediated Necrotizing Myopathy Diagnosis and Flare in an Adolescent After COVID-19 Vaccine.

Patricia Hoffman, Ezra Chefitz, Cynthia Salvant, Daniel B Horton

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Patricia HoffmanDepartment of Pediatrics Rutgers Robert Wood Johnson Medical School New Brunswick New Jersey USA.ORCID https://orcid.org/0009-0009-0199-8259
Ezra ChefitzDepartment of Pediatrics Rutgers Robert Wood Johnson Medical School New Brunswick New Jersey USA.
Cynthia SalvantAlbany Medical Center Albany New York USA.
Daniel B HortonDepartment of Pediatrics Rutgers Robert Wood Johnson Medical School New Brunswick New Jersey USA.ORCID https://orcid.org/0000-0002-1831-1339

Funding

New Jersey Alliance for Clinical Translational Science: NJ ACTSUL1TR003017 · NCATS · RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS · PI PANETTIERI, REYNOLD ALEXANDER · 2019 to 2023
$28.9M
NJ ACTS: A Platform for Translational Science in New JerseyUM1TR004789 · NCATS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Reynold Alexander Panettieri · 2024 to 2026
$16.8M
Safety of Drugs Commonly Used Off-Label in Children Despite Insufficient Evidence of Efficacy and SafetyR01HD109335 · NICHD · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Daniel Benjamin Horton · 2022 to 2026
$3.3M
COVID-19 Network of Networks Expanding Clinical and Translational approaches to Predict Severe Illness in Children (CONNECT to Predict SIck Children)R33HD105619 · NICHD · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI GENNARO, MARIA LAURA, HORTON, DANIEL BENJAMIN · 2023 to 2023
$3.0M
Cohort and biomarkers for COVID-19 severity, natural history, and reinfectionR01AI158911 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI BARRETT, EMILY S, BLASER, MARTIN J · 2021 to 2023
$2.6M
Antibiotics, Juvenile Idiopathic Arthritis, and Antirheumatic Treatment ResponseR01AR074436 · NIAMS · RUTGERS, THE STATE UNIV OF N.J. · PI HORTON, DANIEL BENJAMIN · 2019 to 2022
$2.1M
COVID-19 Network of Networks Expanding Clinical and Translational approaches to Predict Severe Illness in Children (CONNECT to Predict SIck Children)R61HD105619 · NICHD · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI GENNARO, MARIA LAURA, HORTON, DANIEL BENJAMIN · 2021 to 2022
$1.6M
NCATS NIH HHS UL1 TR003017NCATS NIH HHS UM1 TR004789NIAID NIH HHS R01 AI158911NIAMS NIH HHS R01 AR074436NICHD NIH HHS R01 HD109335NICHD NIH HHS R33 HD105619NICHD NIH HHS R61 HD105619
6 · The paper itself

Abstract

We discuss a teenager who developed a rare pediatric autoimmune muscle disease after completing the primary COVID-19 vaccine series, which flared shortly after COVID-19 booster vaccination. This case suggests that a rare chronic pediatric muscle disease may represent a possible adverse event related to COVID-19 vaccination.

Indexed as

COVID‐19inflammatory myopathypediatricsrheumatologyvaccine

Identifiers

PMID41127686
PMCPMC12537298

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.