Evidence map›Paper›PMID 41127611›Full record

ArticleArthroplasty today2025

Validation of Articular Cartilage Depth in Total Knee Arthroplasty.

Evan P Johnson, Nicholas M Brown, Michael D Hellman, Tyler E Calkins, Nuanqiu Hou, John R Crockarell, James L Guyton, Christopher T Holland, William M Mihalko, Marcus C Ford

Abstract read
In one paragraph

Article in Arthroplasty today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Evan P JohnsonDepartment of Orthopaedic Surgery and Biomedical Engineering, The University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA.
Nicholas M BrownDepartment of Orthopaedic Surgery and Rehabilitation, Loyola University Health System, Maywood, IL, USA.
Michael D HellmanSaint Luke's Health System, Rockhill Orthopaedic Specialists, Lee's Summit, MO, USA.
Tyler E CalkinsDepartment of Orthopaedic Surgery and Biomedical Engineering, The University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA.
Nuanqiu HouCampbell Clinic Foundation, Germantown, TN, USA.
John R CrockarellDepartment of Orthopaedic Surgery and Biomedical Engineering, The University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA.
James L GuytonDepartment of Orthopaedic Surgery and Biomedical Engineering, The University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA.
Christopher T HollandDepartment of Orthopaedic Surgery and Biomedical Engineering, The University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA.
William M MihalkoDepartment of Orthopaedic Surgery and Biomedical Engineering, The University of Tennessee Health Science Center-Campbell Clinic, Memphis, TN, USA.
Marcus C FordTexas Hip and Knee Center, Fort Worth, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Understanding cartilage thickness is critical for execution of an unrestricted, calipered kinematic total knee arthroplasty (TKA). Historically, condylar cartilage was assumed to be 2 mm thick. However, thickness may vary based on age, sex, body mass index, anterior cruciate ligament (ACL) status, and alignment. This study aimed to determine in vivo cartilage thickness in patients undergoing TKA and evaluate which factors affect variation. Our hypothesis was in vivo cartilage thickness would be 2 mm on average, but some patients would have greater than 2 mm based on demographic factors. Methods: This multicenter, prospective cross-sectional cohort study evaluated condyle cartilage thickness from resected fragments. Univariate statistics and general linear models were used. Results: Among 806 TKA cases, the mean unworn femoral cartilage thickness was as follows: distal medial 2.0 mm; distal lateral 2.2 mm; posterior medial 2.0 mm; and posterior lateral 2.2 mm. The mean unworn tibia cartilage thickness was as follows: medial spine 2.4 mm; medial center 1.4 mm; lateral spine 2.1 mm; and lateral center 2.5 mm. In patients with unworn femoral cartilage, approximately 18.5% had cartilage greater than 3 mm. In patients with unworn tibial cartilage, approximately 34.7% had cartilage greater than 3 mm. An incompetent ACL was correlated with thinner posteromedial femoral cartilage. Increased thickness was correlated with younger age, men. Conclusions: A subset had unworn cartilage thickness greater than 3.0 mm, supporting our hypothesis. In an ACL deficient knee, the posteromedial cartilage was partially worn and should be considered for MCL isometry. Significant correlations were found based on age, gender, ACL status, alignment, body mass index, and race. Level of Evidence: Level 2, Prospective cohort study.

Indexed as

AlignmentCartilage thicknessTotal knee arthroplasty

Identifiers

PMID41127611
PMCPMC12538020

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.