Evidence map›Paper›PMID 41127557›Full record

ArticleApplied sciences (Basel, Switzerland)2025

Knee Loading Asymmetries During Descent and Ascent Phases of Squatting After ACL Reconstruction.

Manuel Angel Romero Padron, Alyx Jorgensen, David M Werner, Matthew Alan Tao, Elizabeth Wellsandt

Abstract read
In one paragraph

Article in Applied sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manuel Angel Romero PadronDepartment of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, 4014 Leavenworth St., Omaha, NE 68105, USA.
Alyx JorgensenPhysical Therapy Program, University of Nebraska Medical Center, 4014 Leavenworth St., Omaha, NE 68105, USA.
David M WernerCollege of Allied Health Professions, University of Nebraska Medical Center, 3908 Jones St., Omaha, NE 68198, USA.
Matthew Alan TaoDepartment of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, 4014 Leavenworth St., Omaha, NE 68105, USA.
Elizabeth WellsandtDepartment of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, 4014 Leavenworth St., Omaha, NE 68105, USA.ORCID 0000-0003-1983-6812

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ESTABROOKS, PAUL · 2016 to 2025
$42.8M
Knee Arthroplasty Activity Trial (KArAT)R01AR080346 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Elena Losina · 2022 to 2026
$3.6M
Understanding the Neurophysiology of Ankle Instability to Improve Rehabilitation OutcomesR15AG085105 · NIA · UNIVERSITY OF NEBRASKA OMAHA · PI ROSEN, ADAM B · 2024 to 2024
$446k
STepped Exercise Program for Knee Osteoarthritis: The STEP-KOA StudyR34AR083077 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ALLEN, KELLI D., GOLIGHTLY, YVONNE M · 2024 to 2025
$407k
Osteoarthritis After ACL Injury: Establishing Cumulative Joint Loading as a Preventative TargetR21AR075254 · NIAMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WELLSANDT, ELIZABETH A · 2020 to 2021
$373k
NIAMS NIH HHS R01 AR080346NIAMS NIH HHS R21 AR075254NIAMS NIH HHS R34 AR083077NIA NIH HHS R15 AG085105NIGMS NIH HHS U54 GM115458
6 · The paper itself

Abstract

Asymmetries are common during squats following anterior cruciate ligament reconstruction (ACLR). This study examined interlimb loading differences between squat phases at 6 months post-ACLR. Thirty-five participants performed bodyweight squats at self-selected speed and were analyzed using 3D motion capture. Vertical ground reaction force impulse (vGRFi), external knee flexion moment impulse (KFMi) and hip-to-knee flexion moment impulse ratio (HKRi) were calculated, along with interlimb ratios (ILR). Squat phase durations were also recorded. Paired t-tests and ANCOVA (controlling for time) were used to compare biomechanical variables across squat phases. Greater asymmetry was observed during ascent for vGRFi ILR (

Indexed as

ACLbiomechanicsmovement asymmetryneuromuscular controlrehabilitation

Identifiers

PMID41127557
PMCPMC12539646

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.