Evidence map›Paper›PMID 41127550›Full record

ArticleMaterials today. Bio2025

Herb-based multicomponent carrier-free hydrogel with antipyretic and anti-inflammatory dual effects by regulating MAPK and NF-κB signaling pathway.

Penglong Wang, Xuemei Huang, Shaohui Geng, Guangrui Huang, Wenmin Pi, Nana Han, Yaozhi Zhang, Enfan Xiao, Zhimin Lin, Kai Yuan and 2 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Penglong WangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Xuemei HuangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Shaohui GengSchool of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Guangrui HuangSchool of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Wenmin PiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Nana HanSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Yaozhi ZhangSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Enfan XiaoSchool of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Zhimin LinThird Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, 100029, China.
Kai YuanSchool of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Haimin LeiSchool of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, 102488, China.
Anlong XuSchool of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous traditional Herbal medicine (THM) formulas have demonstrated their effectiveness during long-term clinical practices worldwide, offering a rich repository for the discovery of new drug and functional biomaterials. Consequently, the development of therapeutic supramolecular hydrogels based on plant-derived bioactive molecules has garnered significant attention in the field of new drug development. In this study, we developed a well-defined orally supramolecular drug derived from the classic Ma-Xing-Shi-Gan decoction (MXSGD) which has been widely used in China for the treatment of COVID-19 symptoms and acute infectious diseases. The four representative chemical components of MXSGD-pseudoephedrine, amygdalin, glycyrrhizic acid, and Ca

Indexed as

Antipyretic and anti-inflammatoryCarrier-free hydrogelMa-Xing-Shi-Gan decoctionMulticomponentSelf-assembly

Identifiers

PMID41127550
PMCPMC12538044

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.