ArticleFrontiers in dental medicine2025
Global, regional and national burden of deciduous dental caries from 1990 to 2021: analysis of risk factors and prediction of trends in 2035.
Article in Frontiers in dental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Effect of ammonia-free silver fluoride and silver diammine fluoride on immediate microshear bond strength of resin-modified glass ionomer to demineralised primary tooth dentine.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Early childhood caries-related complications in pediatric dental emergencies: a 7-year retrospective study from Romania.Clinical oral investigations · 2026Observational
- Demographic, Geographic, and Temporal Patterns of Adult Dental Emergency Presentations in Arad County, Western Romania.Healthcare (Basel, Switzerland) · 2026Article
- A "family-school-hospital" collaborative oral health management model for preschool children: a prospective single-arm pre-post intervention study.Frontiers in dental medicine · 2026Article
- Effect of silver diamine fluoride versus fluoride varnish in arresting early childhood caries: A clinical study.Bioinformation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/aim: Early childhood caries (ECC) is one of the most prevalent global oral health issues in children under five years old, significantly impacting their overall health and quality of life. This study aimed to analyze the global, regional, and national burden of ECC from 1990 to 2021, identify associated risk factors, and predict trends through 2040. It further examined the influence of socio-demographic factors, sex, and age on ECC incidence and prevalence. Patients and methods: Data from the Global Burden of Disease (GBD) 2021 database were analyzed using Bayesian Meta-Regression models to estimate ECC incidence, prevalence, and years lived with disability (YLDs) across 204 countries and regions. Socio-Demographic Index (SDI) levels, sex, and age-specific trends were assessed. Age-standardized rates and estimated annual percentage changes (EAPCs) were calculated. Predictive models, including ARIMA, were developed to forecast future trends. Results: Between 1990 and 2021, ECC incidence and prevalence showed modest declines globally, with significant variations across SDI regions. High SDI regions exhibited the lowest burden due to effective public health measures, while medium and low SDI regions faced persistent challenges. Sex disparities were observed, with males showing slightly higher rates than females. Children aged 5-9 years bore the highest burden of ECC. Predictions for 2040 indicate a potential rebound in ECC incidence in low and medium SDI regions without targeted interventions. Conclusion: This study highlights the substantial burden of ECC, particularly in under-resourced regions, and underscores the need for tailored public health strategies. Effective prevention, improved healthcare access, and education are critical to reducing ECC burden globally, ensuring better oral health outcomes for children, and addressing disparities across socio-economic, sex, and age groups.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.