Evidence map›Paper›PMID 41127496›Full record

ReviewCureus2025

A Review of Thyroid Rests: From Embryology to Clinical Management.

Ghezlan Aldawas, Sherif Ragab

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ghezlan AldawasDepartment of Otolaryngology, Head and Neck Surgery, Farwaniya Hospital, Kuwait City, KWT.
Sherif RagabDepartment of Otolaryngology, Head and Neck Surgery, Farwaniya Hospital, Kuwait City, KWT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ectopic thyroid tissue (ETT) is a rare developmental anomaly often misidentified as other pathologies like parathyroid adenomas or metastatic lymphadenopathy. This can lead to unnecessary surgical interventions and diagnostic delays. This narrative review aims to synthesize current knowledge on the embryological origins, anatomical distribution, diagnostic challenges, and management strategies of ETT. A comprehensive literature search was conducted by searching PubMed, Google Scholar, and Scopus databases, covering publications from January 2015 to January 2025. Fifteen peer-reviewed publications, including case reports, case series, reviews, and original research, were selected for inclusion. Ectopic thyroid tissue (ETT) most commonly manifests as a lingual thyroid, situated at the base of the tongue. Diagnosis is challenging due to overlapping imaging characteristics with neoplastic or hyperfunctioning parathyroid tissue. A multimodal approach is essential, combining imaging (ultrasound, CT, MRI) with functional assessments (scintigraphy) and histological confirmation (FNA). Management is individualized, with observation for asymptomatic cases and surgical intervention for symptomatic or suspicious lesions. A multidisciplinary team (MDT) approach is critical for accurate diagnosis and to prevent unnecessary procedures. This review underscores the importance of structured diagnostic protocols to improve outcomes for patients with ETT.

Indexed as

ectopic thyroidembryologymisdiagnosismultidisciplinary managementneck massesthyroid rests

Identifiers

PMID41127496
PMCPMC12538268

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.