Evidence map›Paper›PMID 41127412›Full record

ArticleFrontiers in human neuroscience2025

Complex neurological interplay: adult-onset migraine-triggered seizures in schizencephaly-a case report.

Yuzhu Wang, Fu Zhou, Fei Liu, Xiaohui Wu, Xuan Chen, Zhiqin Xi

Abstract readCase Reports
In one paragraph

Article in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuzhu Wang *Department of Neurology, The People's Hospital of Dazu, Chongqing, China.
Fu Zhou *Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Fei LiuDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaohui WuDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xuan ChenDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhiqin XiDepartment of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizencephaly is a rare congenital cerebral malformation typically diagnosed in early childhood due to serious neurological manifestations. Our case report described a patient with open lip schizencephaly, notable for three unique aspects. First, the patient experienced epileptic seizures in adulthood, which is atypical compared to the usual onset in childhood. Additionally, the patient reported migraine-like pain occurring seconds before each epileptic seizure, with a short interval and regular occurrence. Finally, contrary to the expected severity of symptoms in a patient with open lip schizencephaly, the patient was able to live independently in daily activities, maintained normal cognitive function, and effectively managed both seizures and headaches with standard medication. The purpose of this report is to highlight the significant role of schizencephaly as a causative factor in adult-onset epilepsy and to emphasize the need for a comprehensive therapeutic approach addressing both the structural and functional aspects of this complex neurodevelopmental condition (under the premise of schizencephaly, there were migraine-like attacks in the short term before epileptic seizures).

Indexed as

case reportepilepsymigraineschizencephalyseizures

Identifiers

PMID41127412
PMCPMC12537689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.