Evidence map›Paper›PMID 41127408›Full record

ArticleJHLT open2025

Prognostic value of NT-proBNP monitoring in patients with left ventricular assist devices.

Miloud Cherbi, Joaquim Verdaguer, Romain Itier, Laurence Barde, Pauline Fournier, Etienne Grunenwald, Philippe Gaudard, Philippe Rouvière, Adrien Molina, Aurore Ughetto and 1 more

Abstract read
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Miloud CherbiDepartment of Cardiology, Toulouse University Hospital, Toulouse, France.
Joaquim VerdaguerDepartment of Cardiology, Toulouse University Hospital, Toulouse, France.
Romain ItierDepartment of Cardiology, Toulouse University Hospital, Toulouse, France.
Laurence BardeDepartment of Cardiology, Toulouse University Hospital, Toulouse, France.
Pauline FournierDepartment of Cardiology, Toulouse University Hospital, Toulouse, France.
Etienne GrunenwaldDepartment of Cardiac Surgery, Toulouse University Hospital, Toulouse, France.
Philippe GaudardDepartment of Anesthesiology and Critical Care Medicine, Arnaud de Villeneuve Hospital, CHU Montpellier, University of Montpellier, Montpellier, France.
Philippe RouvièreDepartment of Cardiac Surgery, CHU Montpellier, University of Montpellier, Montpellier, France.
Adrien MolinaDepartment of Cardiac Surgery, CHU Montpellier, University of Montpellier, Montpellier, France.
Aurore UghettoDepartment of Anesthesiology and Critical Care Medicine, Arnaud de Villeneuve Hospital, CHU Montpellier, University of Montpellier, Montpellier, France.
Clément DelmasDepartment of Cardiology, Toulouse University Hospital, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: N-terminal fragment of the brain natriuretic peptide (NT-proBNP) is a well-established biomarker in heart failure; however, its prognostic value in patients supported by left ventricular assist devices (LVAD) remains unclear. Methods: We conducted a retrospective cohort study including patients implanted with an LVAD between 2008 and 2025 at 2 tertiary care centers. NT-proBNP levels were measured at 3 and 6 months postimplantation, and their relationships with invasive hemodynamic parameters and 1-year clinical outcomes were evaluated at each time point. Results: A total of 128 patients were included. Whereas NT-proBNP measured at 3 months showed no significant correlation with any hemodynamic parameters, NT-proBNP at 6 months correlated with right atrial pressure (ρ = 0.46, Conclusions: NT-proBNP measured at 6 months post-LVAD implantation is a significant predictor of adverse clinical and hemodynamic outcomes at 1 year, supporting its role in risk stratification. Prospective studies are warranted to validate these findings.

Indexed as

advanced heart failureBNPLVADmonitoringNT-proBNPoutcomes

Identifiers

PMID41127408
PMCPMC12538486

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.