SynthesisFrontiers in neurology2025
The effectiveness of digital cognitive intervention in patients with traumatic brain injury: systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Immersive Technologies for Cognitive Rehabilitation in Dementia and Mild Cognitive Impairment: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Predictors of Return to Driving in Patients With Acquired Brain Injury: A Systematic Review With Meta-Analysis.Occupational therapy international · 2026Pooled it
- Memory Impairments: Type, Causes, and Molecular Players-Memory Dysfunction Across Neurologic Insults.Cells · 2026Review
- Efficacy of Technology-Based Cognitive Rehabilitation Tools for Cancer-Related Cognitive Impairment in Non-CNS Cancer Patients: A Systematic Review.Healthcare (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This meta-analysis aims to quantitatively evaluate the effects of digital cognitive intervention (non-immersive computer- and immersive virtual reality (VR)-based) on cognitive function and psychosocial outcomes in patients with traumatic brain injury (TBI), and to explore potential moderating factors. Methods: A systematic search was conducted in PubMed, the Cochrane Library, Embase, and Web of Science databases from their inception to April 3, 2025. Standardized mean differences (SMDs) and 95% confidence intervals (CIs) were calculated to estimate effect sizes, and heterogeneity was assessed using the I Results: A total of 16 studies were included; 9 employed computer-based cognitive interventions and 7 used VR-based interventions. The results showed that both types of interventions significantly improved global cognitive function (SMD: 0.64, 95% CI: 0.44 to 0.85, I Conclusion: This meta-analysis supports the efficacy of digital cognitive intervention in improving cognitive function in TBI patients. We recommend individualized treatment programs to more effectively address cognitive impairments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.