Evidence map›Paper›PMID 41127263›Full record

ArticleResearch (Washington, D.C.)2025

Multichannel 3D-Printed Bioactive Scaffold Combined with Small Interfering RNA Delivery to Promote Neurological Recovery after Spinal Cord Injury.

Jingjia Ye, Fenglu Li, Zhengfa Wen, Junsheng He, Gaoxing Pan, Xinrang Zhai, Linran Song, Xianzhu Zhang, Xuefei Zhou, Xudong Yao and 3 more

Abstract read
In one paragraph

Article in Research (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Novel Composite Conduits for Long-Distance Peripheral Nerve Repair.Polymer science & technology (Washington, D.C.) · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jingjia YeDepartment of Orthopedics, Center for Regeneration and Aging Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, 322000, P. R. China.
Fenglu LiQingyuan Innovation Laboratory, 1 Xueyuan Road, Quanzhou 362801, P. R. China.
Zhengfa WenDepartment of Orthopedics, Center for Regeneration and Aging Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, 322000, P. R. China.
Junsheng HeDepartment of Orthopedics, Center for Regeneration and Aging Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, 322000, P. R. China.
Gaoxing PanQingyuan Innovation Laboratory, 1 Xueyuan Road, Quanzhou 362801, P. R. China.
Xinrang ZhaiSchool of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu, 210094, P. R. China.
Linran SongDepartment of Orthopedics, Center for Regeneration and Aging Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, 322000, P. R. China.
Xianzhu ZhangDepartment of Sports Medicine of the The First Affiliated Hospital, and Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou 310003, P. R. China.
Xuefei ZhouDepartment of Sports Medicine of the The First Affiliated Hospital, and Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou 310003, P. R. China.
Xudong YaoDepartment of Orthopedics, Center for Regeneration and Aging Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, 322000, P. R. China.
Yanlang WangSchool of Advanced Manufacturing, Fuzhou University,, Jinjiang 362200, P. R. China.
Jin ZhangQingyuan Innovation Laboratory, 1 Xueyuan Road, Quanzhou 362801, P. R. China.ORCID https://orcid.org/0000-0002-0074-868X
Wei WeiDepartment of Orthopedics, Center for Regeneration and Aging Medicine, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, Zhejiang, 322000, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhancing axonal regeneration holds promise for restoring neural circuits and locomotion function after spinal cord injury (SCI), while precise guidance of micrometer-scale axons to their natural regions remains a critical challenge. To address this problem, we developed an integrated 3D-printed scaffold featuring internal parallel channels infused with a bioactive hydrogel containing laminin-derived chimeric RADA

Identifiers

PMID41127263
PMCPMC12538118

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.