Evidence map›Paper›PMID 41127225›Full record

SynthesisSultan Qaboos University medical journal2025

Effect of Adjuvant Vitamin D Therapy on Total Nasal Symptoms Score, IgE, and Eosinophil Levels in Allergic Rhinitis: A systematic review and meta-analysis.

Rahmi Surayya, Dwi R Pawarti, Rizka F Perdana, Citrawati D K Wungu

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Sultan Qaboos University medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rahmi SurayyaDepartment of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Malikussaleh, Aceh Utara, Indonesia.ORCID 0009-0006-0785-3964
Dwi R PawartiDepartment of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0001-9775-3815
Rizka F PerdanaDepartment of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0002-8327-9160
Citrawati D K WunguDepartment of Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.ORCID 0000-0001-5180-957X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review investigated the effects of adjuvant vitamin D therapy on Total Nasal Symptoms Score (TNSS), IgE, and eosinophil counts in patients with allergic rhinitis (AR). The meta-analysis used databases, such as PubMed, Science Direct, Scopus, Web of Science, SAGE journals, and clinicaltrials.gov. Quality appraisal was performed using RoB 2 and NOS tools. The research was guided by the PRISMA 2020 chart and analyzed using RevMan 5.4. Sixteen articles, including 11 randomised controlled trials and five cohorts, met the inclusion criteria. Fourteen articles reported TNSS, while four reported IgE and eosinophil levels. Vitamin D significantly reduced TNSS (SMD -2.24; 95% confidence interval [CI]: -3.05, -1.43;

Indexed as

EosinophilsImmunoglobulin ERhinitis, AllergicVitamin DHumansImmunoglobulin EVitamin DAllergic RhinitisEosinophilsImmunoglobulin EMeta-AnalysisNasal ObstructionRhinorrheaSneezingVitamin D

Identifiers

PMID41127225
PMCPMC12538924

What OpenQuestion holds

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LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.