ArticleRSC advances2025
Discovery of novel angiotensin-converting enzyme inhibitory peptides by
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Hypertension represents a crucial risk factor in the development of cardiovascular diseases, including heart failure, stroke, coronary heart disease and myocardial infarction. Currently, synthetic angiotensin-converting enzyme (ACE) inhibitors are an important first-line treatment for hypertension. However, these synthetic ACE inhibitors often produce side effects in clinical application, such as cough, gustatory disturbance and skin rash. Thus, it is urgent to find safe and effective ACE inhibitors for the treatment of hypertension. Therefore, a series of ACE inhibitory peptides were studied using computational approaches. Initially, a reliable 3D-QSAR model was derived based on CoMFA (
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Registered trials
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