ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2025
Effect of introducing a pharmacist-led support system on the administration rate of vancomycin loading dose and the 0-24-hour area under the concentration-time curve.
Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Vancomycin-associated acute kidney injury in patients with moderate CKD: a multicentre retrospective cohort study.JAC-antimicrobial resistance · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to evaluate the impact of a pharmacist-led support system on the administration rate of vancomycin (VCM) loading dose, 0-24-hour area under the concentration-time curve (AUC Design: This retrospective study with interrupted time series analysis was conducted from January 2021 to May 2024. Setting: A public tertiary referral center providing acute and specialized inpatient care in Japan. Patients: Among the 587 hospitalized patients who received VCM during the study period, 326 were evaluated. Intervention: The intervention comprised implementation of a pharmacist-led support system involving prospective prescription review and direct intervention when a VCM loading dose (25-30 mg/kg) was not prescribed. Results: The loading dose administration rate increased significantly by 43.2% immediately introducing the support system (95% confidence interval: 8.40-77.90; Conclusions: The support system improved the loading dose administration rate and AUC
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Registered trials
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