Evidence map›Paper›PMID 41127052›Full record

ArticleJournal of extracellular biology2025

Outer Membrane Vesicles From

Aadil Sheikh, Colin Scano, Julia Xu, Tolulope Ojo, Jessica M Conforti, Kayla L Haberman, Bryan King, Alysia S Martinez, Michelle Pujol, Juli Watkins and 11 more

Abstract read
In one paragraph

Article in Journal of extracellular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Outer membrane vesicles secreted byInfection and immunity · 2026
    Article
  2. Dual immunomodulatory effects ofFrontiers in microbiology · 2026
    Article
  3. Article
  4. Outer Membrane Vesicles FromJournal of extracellular biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Aadil SheikhDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0000-0001-6246-3439
Colin ScanoDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0009-0000-9422-4475
Julia XuDepartment of Biology Baylor University Waco USA.
Tolulope OjoDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0009-0002-1761-7165
Jessica M ConfortiDepartment of Chemistry & Biochemistry Baylor University Waco USA.ORCID https://orcid.org/0009-0001-0743-670X
Kayla L HabermanDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0009-0006-0832-8694
Bryan KingDepartment of Biology Baylor University Waco USA.
Alysia S MartinezDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0009-0002-8003-9652
Michelle PujolDepartment of Biology Baylor University Waco USA.
Juli WatkinsDepartment of Biology Baylor University Waco USA.
James LotterDepartment of Biology Baylor University Waco USA.
Emily L LinDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0000-0002-9385-048X
Bernd ZechmannCenter for Microscopy and Imaging Baylor University Waco USA.
Amanda SevcikDepartment of Environmental Sciences Baylor University Waco USA.
Christie SayesDepartment of Microbiology and Immunology Drexel University Philadelphia USA.
Elyssia S GallagherDepartment of Chemistry & Biochemistry Baylor University Waco USA.
Steven P LangDepartment of Microbiology and Immunology Drexel University Philadelphia USA.
Joshua MellDepartment of Microbiology and Immunology Drexel University Philadelphia USA.
Garth D EhrlichDepartment of Microbiology and Immunology Drexel University Philadelphia USA.
Joseph H TaubeDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0000-0002-3636-5189
K Leigh GreathouseDepartment of Biology Baylor University Waco USA.ORCID https://orcid.org/0000-0002-6855-8516

Funding

Assessing the Biomolecular Structures that Result from Electrospray IonizationR35GM150464 · NIGMS · BAYLOR UNIVERSITY · PI Elyssia S Gallagher · 2023 to 2026
$1.4M
KDM6A function in epithelial-mesenchymal plasticityR15GM146188 · NIGMS · BAYLOR UNIVERSITY · PI TAUBE, JOSEPH H. · 2022 to 2023
$493k
Decoding the Role of Bacterial Outer Membrane Vesicle and Small RNAs in Host InflammationR15AI156742 · NIAID · BAYLOR UNIVERSITY · PI GREATHOUSE, LEIGH · 2021 to 2021
$420k
NIAID NIH HHS R15 AI156742NIGMS NIH HHS R15 GM146188NIGMS NIH HHS R35 GM150464
6 · The paper itself

Abstract

Alterations to the community structure and function of the microbiome are associated with changes to host physiology, including immune responses. However, the contribution of microbe-derived RNAs carried by outer membrane vesicles (OMVs) to host immune responses remains unclear. This study investigated the role of OMVs and OMV-associated small RNA (sRNA) species from pathogenic and commensal

Indexed as

Bacteroides fragilisouter membrane vesiclessmall RNA

Identifiers

PMID41127052
PMCPMC12538813

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.