Evidence map›Paper›PMID 41127014›Full record

ReviewFrontiers in oncology2025

MicroRNAs and lung cancer: overview of essential pathways and somatic mutations in cancer progression.

Andrei-Alexandru Tirpe, Andreea Nutu, Constantin Busuioc, Ovidiu-Laurean Pop, Ioana Berindan-Neagoe

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrei-Alexandru TirpeDepartment of Genomics, MEDFUTURE Institute for Biomedical Research, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Andreea NutuDepartment of Genomics, MEDFUTURE Institute for Biomedical Research, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Constantin BusuiocDepartment of Pathology, National Institute of Infectious Disease, Bucharest, Romania.
Ovidiu-Laurean PopDepartment of Morphological Sciences, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
Ioana Berindan-NeagoeDepartment of Genomics, MEDFUTURE Institute for Biomedical Research, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the most frequently diagnosed type of cancer worldwide, according to GLOBOCAN 2022 statistics. Key genetic alterations involve driver gene mutations that significantly enhance cancer aggressiveness. These include several

Indexed as

cancer progressionlung cancermicroRNAmiRNAsignaling cascadetargeted therapy

Identifiers

PMID41127014
PMCPMC12537385

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.