Evidence map›Paper›PMID 41127004›Full record

ArticleMolecular therapy. Methods & clinical development2025

A novel gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types.

Cato Prince, George Bounoutas, Bolu Zhou, Waseem Raja, Isabella Gold, Riana Pozsgai, Parmi Thakker, Nicole Boisvert, Christopher Reardon, Stephanie Thurmond and 15 more

Abstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Anellovirus protein encoded byProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Cato PrinceRing Therapeutics, Cambridge, MA, USA.
George BounoutasRing Therapeutics, Cambridge, MA, USA.
Bolu ZhouRing Therapeutics, Cambridge, MA, USA.
Waseem RajaRing Therapeutics, Cambridge, MA, USA.
Isabella GoldRing Therapeutics, Cambridge, MA, USA.
Riana PozsgaiRing Therapeutics, Cambridge, MA, USA.
Parmi ThakkerRing Therapeutics, Cambridge, MA, USA.
Nicole BoisvertRing Therapeutics, Cambridge, MA, USA.
Christopher ReardonRing Therapeutics, Cambridge, MA, USA.
Stephanie ThurmondRing Therapeutics, Cambridge, MA, USA.
Erin OzturkRing Therapeutics, Cambridge, MA, USA.
Rajendra BoggavarapuRing Therapeutics, Cambridge, MA, USA.
Jenna Antonucci JohnsonRing Therapeutics, Cambridge, MA, USA.
Patricio JeraldoRing Therapeutics, Cambridge, MA, USA.
Simeon SpringerRing Therapeutics, Cambridge, MA, USA.
Lovepreet ChahalRing Therapeutics, Cambridge, MA, USA.
Emily SteadRing Therapeutics, Cambridge, MA, USA.
Cameron DodierRing Therapeutics, Cambridge, MA, USA.
Bryan VoughtRing Therapeutics, Cambridge, MA, USA.
Maciej NogalskiRing Therapeutics, Cambridge, MA, USA.
Dhananjay NawandarRing Therapeutics, Cambridge, MA, USA.
Christopher WrightRing Therapeutics, Cambridge, MA, USA.
Ashley MackeyRing Therapeutics, Cambridge, MA, USA.
Geoffrey ParsonsRing Therapeutics, Cambridge, MA, USA.
Joseph CabralRing Therapeutics, Cambridge, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anelloviruseyegene therapyhippocampusviral vector

Identifiers

PMID41127004
PMCPMC12538900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.