Evidence map›Paper›PMID 41126762›Full record

ReviewBJPsych bulletin2025

The importance of safe lithium plasma monitoring in older people.

Judy S Rubinsztein, Steven Willis, Harleen Birgi, Kapila Sachdev, Christopher Southwell, Andrew P Stewart, John T O'Brien

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BJPsych bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Judy S RubinszteinDepartment of Psychiatry, https://ror.org/013meh722University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0003-1466-3553
Steven WillisNorfolk and Suffolk NHS Foundation Trust, Bury, UK.
Harleen BirgiEast London NHS Foundation Trust, London, UK.
Kapila SachdevEast London NHS Foundation Trust, London, UK.
Christopher SouthwellCraigavon Area Hospital, Portadown, Northern Ireland.
Andrew P StewartCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
John T O'BrienDepartment of Psychiatry, https://ror.org/013meh722University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0002-0837-5080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We consider that the current National Institute for Health and Care Excellence (NICE) guideline CG185 on bipolar disorder does not provide sufficiently specific guidance for the safe monitoring of plasma lithium levels in older people. We feel this needs correction, and laboratories across the UK should lower the range recommended for monitoring older people's lithium levels in line with guidelines from the International Society for Bipolar Disorder. This would provide a safety net in older people in order to prevent lithium toxicity without compromising efficacy.

Indexed as

bipolar type I or II disordersLithiumold age psychiatryrecurrent unipolar depressionrenal failure

Identifiers

PMID41126762
PMCPMC13386308

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.