ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
A Hybrid Diffusion Model Enhances Multiparametric 3D Photoacoustic Computed Tomography.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Volumetric photoacoustic imaging of elastin and age-related remodeling using near-infrared probe ElaNIR.Photoacoustics · 2026Article
- Review
- Electrically switchable dual-focus metalens for depth-extended in vivo photoacoustic imaging of ophthalmic vascular disease.Light, science & applications · 2026Article
- Deep Learning for scaling large-aperture photoacoustic computed tomography : From single fingers to the human hand.Ultrasonics · 2026Article
- Multiscale photoacoustic imaging of stroke in preclinical models and future directions toward clinical translation [Invited].Biomedical optics express · 2026Review
- HER2 Score-Aware Virtual Immunohistochemistry via Non-Contrastive Multi-Task Translation.Diagnostics (Basel, Switzerland) · 2026Article
- A Hybrid Diffusion Model Enhances Multiparametric 3D Photoacoustic Computed Tomography.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ultrasonic modulation of brain glymphatic transport: from observations to theranostic applications.Cancer drug resistance (Alhambra, Calif.) · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Photoacoustic computed tomography (PACT) reveals biological structures, pharmacokinetics, and physiological functions. Although a premium PACT system with many ultrasound (US) transducers delivers high-quality volumetric imaging, it suffers from high system costs and slow temporal resolution. Here, using a limited number of US elements, a hybrid diffusion model (HD-PACT) is demonstrated that enhances dynamic multiparametric (structural, functional, and contrast-enhanced) 3D PACT. Using just 256 out of the 1024 elements in a premier hemispherical US array for PACT, HD-PACT improves structural images acquired in different planes, organisms, and wavelengths. In functional imaging, HD-PACT enables 256-element PACT to observe hypoxia, pharmacokinetics, and angiogenesis during tumor progression. Lastly, HD-PACT is transferable to low-end PACT (only 128 US elements), where it dynamically captures contrast-free/enhanced organs, oxygen-perturbed brains, and cardiac dynamics with high spatiotemporal resolution in live animals. It is believed that HD-PACT will be valuable in oncology, cardiology, pharmacology, and endocrinology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.